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• W2017232237 abstract "The spread of multiresistant Gram positive bacteria required the development of new drugs. Linezolid, a new oxazolidinone, is active against these pathogens and is marketed for the treatment of severe glycopeptides-resistant Gram positive-bacteria in adults. Moreover, the availability of intravenous and oral formulation with an excellent bioavailability of the latter, is hoped to facilitate the management of these infections. Most information regarding the pharmacoketic profile, efficacy and tolerability of linezolid in pediatric derived from adults studies. In this review we summarize evidence regarding the uses of linezolid in children focusing on the clinical efficacy data and safety in serious Gram-positive infections and also in compassional uses." @default.
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• W2017232237 date "2010-09-01" @default.
• W2017232237 modified "2023-10-16" @default.
• W2017232237 title "Le linézolide en pédiatrie" @default.
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• W2017232237 doi "https://doi.org/10.1016/s0929-693x(10)70914-3" @default.
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