Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017242016> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2017242016 abstract "Viruses contained in live-attenuated virus vaccines (LAVV) can be transmitted between individuals, resulting in secondary or contact vaccinations. This fact has been exploited successfully in the use of the Oral Polio Vaccine (OPV) to better control wild-type polio viruses. In this work we analyze general LAVV vaccination models for infections that confer lifelong immunity. We consider both standard (continuous) vaccination strategies and pulse vaccination programs (where mass vaccination is carried out at regular intervals). For continuous vaccination, we provide a complete global analysis of a very general compartmental ordinary differential equation LAVV model. We find that the threshold vaccination level required for the eradication of wild-type virus depends on the basic reproduction numbers of both the wild-type and vaccine viruses, but is otherwise independent of the distributions of the durations in each of the sequence of stages of disease progression (e.g., latent, infectious, etc.). Furthermore, even for vaccine viruses with reproduction numbers below one, which would naturally fade from the population upon cessation of vaccination, there can be a significant reduction in the threshold vaccination level. The dependence of the threshold vaccination level on the virus reproduction numbers largely generalizes to the pulse vaccination model. For shorter pulsing periods there is negligible difference in threshold vaccination level as compared to continuous vaccination campaigns. Thus, we conclude that current policy in many countries to employ annual pulsed OPV vaccination does not significantly diminish the benefits of contact vaccination." @default.
- W2017242016 created "2016-06-24" @default.
- W2017242016 creator A5065405992 @default.
- W2017242016 creator A5077626949 @default.
- W2017242016 date "2010-03-01" @default.
- W2017242016 modified "2023-09-27" @default.
- W2017242016 title "Population dynamics of live-attenuated virus vaccines" @default.
- W2017242016 cites W1510122527 @default.
- W2017242016 cites W1606697907 @default.
- W2017242016 cites W1964273550 @default.
- W2017242016 cites W1969178891 @default.
- W2017242016 cites W1969616932 @default.
- W2017242016 cites W1975708886 @default.
- W2017242016 cites W1998564383 @default.
- W2017242016 cites W2000544872 @default.
- W2017242016 cites W2012620166 @default.
- W2017242016 cites W2030167963 @default.
- W2017242016 cites W2039834143 @default.
- W2017242016 cites W2041572706 @default.
- W2017242016 cites W2057761253 @default.
- W2017242016 cites W2059685481 @default.
- W2017242016 cites W2060195907 @default.
- W2017242016 cites W2067594212 @default.
- W2017242016 cites W2072689735 @default.
- W2017242016 cites W2097433287 @default.
- W2017242016 cites W2103937124 @default.
- W2017242016 cites W2107407339 @default.
- W2017242016 cites W2112680994 @default.
- W2017242016 cites W2124441204 @default.
- W2017242016 cites W2150437808 @default.
- W2017242016 cites W2160057076 @default.
- W2017242016 cites W2161728228 @default.
- W2017242016 cites W2479395228 @default.
- W2017242016 cites W580296679 @default.
- W2017242016 cites W1984886828 @default.
- W2017242016 doi "https://doi.org/10.1016/j.tpb.2009.08.003" @default.
- W2017242016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19735670" @default.
- W2017242016 hasPublicationYear "2010" @default.
- W2017242016 type Work @default.
- W2017242016 sameAs 2017242016 @default.
- W2017242016 citedByCount "6" @default.
- W2017242016 countsByYear W20172420162014 @default.
- W2017242016 countsByYear W20172420162016 @default.
- W2017242016 countsByYear W20172420162020 @default.
- W2017242016 crossrefType "journal-article" @default.
- W2017242016 hasAuthorship W2017242016A5065405992 @default.
- W2017242016 hasAuthorship W2017242016A5077626949 @default.
- W2017242016 hasConcept C104317684 @default.
- W2017242016 hasConcept C159047783 @default.
- W2017242016 hasConcept C204264503 @default.
- W2017242016 hasConcept C22070199 @default.
- W2017242016 hasConcept C2908647359 @default.
- W2017242016 hasConcept C4870876 @default.
- W2017242016 hasConcept C54355233 @default.
- W2017242016 hasConcept C54602769 @default.
- W2017242016 hasConcept C60987743 @default.
- W2017242016 hasConcept C71924100 @default.
- W2017242016 hasConcept C86803240 @default.
- W2017242016 hasConcept C99454951 @default.
- W2017242016 hasConceptScore W2017242016C104317684 @default.
- W2017242016 hasConceptScore W2017242016C159047783 @default.
- W2017242016 hasConceptScore W2017242016C204264503 @default.
- W2017242016 hasConceptScore W2017242016C22070199 @default.
- W2017242016 hasConceptScore W2017242016C2908647359 @default.
- W2017242016 hasConceptScore W2017242016C4870876 @default.
- W2017242016 hasConceptScore W2017242016C54355233 @default.
- W2017242016 hasConceptScore W2017242016C54602769 @default.
- W2017242016 hasConceptScore W2017242016C60987743 @default.
- W2017242016 hasConceptScore W2017242016C71924100 @default.
- W2017242016 hasConceptScore W2017242016C86803240 @default.
- W2017242016 hasConceptScore W2017242016C99454951 @default.
- W2017242016 hasLocation W20172420161 @default.
- W2017242016 hasLocation W20172420162 @default.
- W2017242016 hasOpenAccess W2017242016 @default.
- W2017242016 hasPrimaryLocation W20172420161 @default.
- W2017242016 hasRelatedWork W1966207826 @default.
- W2017242016 hasRelatedWork W1983105176 @default.
- W2017242016 hasRelatedWork W2003788758 @default.
- W2017242016 hasRelatedWork W2028013595 @default.
- W2017242016 hasRelatedWork W2028449304 @default.
- W2017242016 hasRelatedWork W2040719907 @default.
- W2017242016 hasRelatedWork W2044738449 @default.
- W2017242016 hasRelatedWork W2051912669 @default.
- W2017242016 hasRelatedWork W2067574622 @default.
- W2017242016 hasRelatedWork W2150945177 @default.
- W2017242016 hasRelatedWork W2381944992 @default.
- W2017242016 hasRelatedWork W2392108954 @default.
- W2017242016 hasRelatedWork W2756072099 @default.
- W2017242016 hasRelatedWork W2999103442 @default.
- W2017242016 hasRelatedWork W3015081015 @default.
- W2017242016 hasRelatedWork W3041985995 @default.
- W2017242016 hasRelatedWork W3106023982 @default.
- W2017242016 hasRelatedWork W3107731651 @default.
- W2017242016 hasRelatedWork W3165053077 @default.
- W2017242016 hasRelatedWork W3208631917 @default.
- W2017242016 isParatext "false" @default.
- W2017242016 isRetracted "false" @default.
- W2017242016 magId "2017242016" @default.
- W2017242016 workType "article" @default.