Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017244116> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2017244116 endingPage "509" @default.
- W2017244116 startingPage "497" @default.
- W2017244116 abstract "Alteration of metabolism of taurine in prolonged light- and dark-adapted frog retinae were studied in comparison with that of gamma-aminobutyric acid (GABA) and the following results were obtained. (1) Statistically significant alterations in retinal taurine, an increase in dark-adapted, and a decrease in light-adapted states, respectively, occurred when frogs were adapted continuously to light or dark for more than 3 weeks. Under the same experimental conditions, no alteration in retinal GABA was noted. (2) At 3 weeks and thereafter, a significant increase of retinal cysteine sulfinic acid decarboxylase (CSD; EC 4.1.1.12) activity, an enzyme involved in the biosynthetic pathway of taurine, also occurred in the dark, whereas the activity in the light-adapted retina was reduced. On the other hand, the retinal activity of L-glutamate decarboxylase (GAD; EC 4.1.1.15), the rate-limiting enzyme of GABA biosynthesis, was not altered in dark- as well as light-adapted state. Similarly, retinal GABA-transaminase (GABA-T; EC 2.6.1.19)-succinic semialdehyde dehydrogenase (SSADH; EC 1.2.1.16) was unaltered. (3) These alterations in retinal taurine were, however, unaccompanied by any changes in factors related to transmitter actions such as evoked release, high affinity uptake, and specific binding to synaptic membranes. The above results suggest that, different from GABA as a potent candidate for inhibitory neurotransmitter, retinal taurine may act as neuromodulator and/or may play an important role as a basic factor for maintaining cellular integrity under certain pathophysiological conditions." @default.
- W2017244116 created "2016-06-24" @default.
- W2017244116 creator A5008702309 @default.
- W2017244116 creator A5027191467 @default.
- W2017244116 creator A5034511140 @default.
- W2017244116 creator A5041110237 @default.
- W2017244116 date "1981-01-01" @default.
- W2017244116 modified "2023-10-18" @default.
- W2017244116 title "Alteration of metabolism of retinal taurine following prolonged light and dark adaptation: A quantitative comparison with gamma-aminobutyric acid (GABA)" @default.
- W2017244116 cites W1775749144 @default.
- W2017244116 cites W1964535311 @default.
- W2017244116 cites W1966387759 @default.
- W2017244116 cites W1968873198 @default.
- W2017244116 cites W1977130035 @default.
- W2017244116 cites W1980746675 @default.
- W2017244116 cites W2010342368 @default.
- W2017244116 cites W2010668351 @default.
- W2017244116 cites W2012667202 @default.
- W2017244116 cites W2021873218 @default.
- W2017244116 cites W2036878977 @default.
- W2017244116 cites W2053283927 @default.
- W2017244116 cites W2058036984 @default.
- W2017244116 cites W2060670810 @default.
- W2017244116 cites W2061448472 @default.
- W2017244116 cites W2075693026 @default.
- W2017244116 cites W2079956880 @default.
- W2017244116 cites W2080346595 @default.
- W2017244116 cites W2081453098 @default.
- W2017244116 cites W2081960409 @default.
- W2017244116 cites W2083557125 @default.
- W2017244116 cites W2145761252 @default.
- W2017244116 cites W2146740809 @default.
- W2017244116 doi "https://doi.org/10.1002/jnr.490060407" @default.
- W2017244116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6975381" @default.
- W2017244116 hasPublicationYear "1981" @default.
- W2017244116 type Work @default.
- W2017244116 sameAs 2017244116 @default.
- W2017244116 citedByCount "4" @default.
- W2017244116 countsByYear W20172441162014 @default.
- W2017244116 crossrefType "journal-article" @default.
- W2017244116 hasAuthorship W2017244116A5008702309 @default.
- W2017244116 hasAuthorship W2017244116A5027191467 @default.
- W2017244116 hasAuthorship W2017244116A5034511140 @default.
- W2017244116 hasAuthorship W2017244116A5041110237 @default.
- W2017244116 hasConcept C126322002 @default.
- W2017244116 hasConcept C134018914 @default.
- W2017244116 hasConcept C169760540 @default.
- W2017244116 hasConcept C170493617 @default.
- W2017244116 hasConcept C181199279 @default.
- W2017244116 hasConcept C185592680 @default.
- W2017244116 hasConcept C2777093970 @default.
- W2017244116 hasConcept C2777771985 @default.
- W2017244116 hasConcept C2779701627 @default.
- W2017244116 hasConcept C2780827179 @default.
- W2017244116 hasConcept C515207424 @default.
- W2017244116 hasConcept C55493867 @default.
- W2017244116 hasConcept C61174792 @default.
- W2017244116 hasConcept C71924100 @default.
- W2017244116 hasConcept C86803240 @default.
- W2017244116 hasConcept C9497952 @default.
- W2017244116 hasConceptScore W2017244116C126322002 @default.
- W2017244116 hasConceptScore W2017244116C134018914 @default.
- W2017244116 hasConceptScore W2017244116C169760540 @default.
- W2017244116 hasConceptScore W2017244116C170493617 @default.
- W2017244116 hasConceptScore W2017244116C181199279 @default.
- W2017244116 hasConceptScore W2017244116C185592680 @default.
- W2017244116 hasConceptScore W2017244116C2777093970 @default.
- W2017244116 hasConceptScore W2017244116C2777771985 @default.
- W2017244116 hasConceptScore W2017244116C2779701627 @default.
- W2017244116 hasConceptScore W2017244116C2780827179 @default.
- W2017244116 hasConceptScore W2017244116C515207424 @default.
- W2017244116 hasConceptScore W2017244116C55493867 @default.
- W2017244116 hasConceptScore W2017244116C61174792 @default.
- W2017244116 hasConceptScore W2017244116C71924100 @default.
- W2017244116 hasConceptScore W2017244116C86803240 @default.
- W2017244116 hasConceptScore W2017244116C9497952 @default.
- W2017244116 hasIssue "4" @default.
- W2017244116 hasLocation W20172441161 @default.
- W2017244116 hasLocation W20172441162 @default.
- W2017244116 hasOpenAccess W2017244116 @default.
- W2017244116 hasPrimaryLocation W20172441161 @default.
- W2017244116 hasRelatedWork W10601204 @default.
- W2017244116 hasRelatedWork W1496486528 @default.
- W2017244116 hasRelatedWork W1931347800 @default.
- W2017244116 hasRelatedWork W1968369052 @default.
- W2017244116 hasRelatedWork W2025227661 @default.
- W2017244116 hasRelatedWork W2052411195 @default.
- W2017244116 hasRelatedWork W2069782349 @default.
- W2017244116 hasRelatedWork W2071941638 @default.
- W2017244116 hasRelatedWork W2080346595 @default.
- W2017244116 hasRelatedWork W2388958639 @default.
- W2017244116 hasVolume "6" @default.
- W2017244116 isParatext "false" @default.
- W2017244116 isRetracted "false" @default.
- W2017244116 magId "2017244116" @default.
- W2017244116 workType "article" @default.