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- W2017250053 abstract "Abstract The involvement of genome portions replicating at different times of the S phase in the control of cell cycle events was analysed in Allium cepa L meristematic cells. 5-Azacytidine (5-azaC) was incorporated into discrete replicating DNA portions in synchronous cells. Cells treated with 5-azaC during the late S phase went through normal cell cycles while cells treated with 5-azaC during the early S phase were able to go through the immediately succeeding mitosis, as well as to begin the subsequent S phase. However, they were unable to enter a second mitosis. Thus, sequences replicating in the early S phase appear to code for a mitotic inhibitor which represses the emergence of a positive mitotic signal. This inhibition took place in the first half of the interphase ( ie during G1) and resulted in a cell cycle blockage in G2." @default.
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- W2017250053 modified "2023-09-27" @default.
- W2017250053 title "Early replicating DNA involved in the G2 to M transition in Allium cepa L meristematic cells" @default.
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- W2017250053 doi "https://doi.org/10.1016/0248-4900(96)89937-0" @default.
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