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- W2017258648 abstract "1. The uptake of 47Ca and 65Zn by bone powder and by inorganic bone was determined in the presence of various carriers. The uptake of 65Zn by bone powder shaken for 2 h at pH 6 with solutions of the radioisotopes, whether without added carrier or in the presence of 2.5 mM of stable calcium, was about 90%, greatly exceeding the uptake of 47Ca. The addition of 2.5 mM of zinc carrier, however, decreased the uptake of both 65Zn and 47Ca. 2. The uptake of 65Zn by inorganic bone was even greater than that by bone powder, approaching 100% in 5 min, and made it clear that the mineral part of bone showed a great preference for 65Zn. 3. Experiments on radioisotope uptake at pH 7.0, in the presence of creatinine to prevent precipitation of the zinc, gave results similar to those obtained at pH 6. 4. The uptake of 65Zn by bone was reduced by ethylenediaminetetraacetic acid, a strong chelating agent, to about 0.3% at pH values from 5 to 9, while the uptake of 65Zn by inorganic bone was reduced under the same conditions to about 1%. 5. The effect of natural chelating agents in binding serum zinc explains why zinc does not occur in even higher concentrations than are actually found in bones and teeth." @default.
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- W2017258648 date "1967-12-27" @default.
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- W2017258648 title "The reaction of 65Zn with the surfaces of bone and bone mineral" @default.
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