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- W2017265557 abstract "The initiation of antibody responses to foreign antigens requires that B cells receive and integrate a variety of signals through an array of cell surface receptors including the B cell antigen receptor (BCR) as well as a number of essential coreceptors. Recent evidence indicates that cholesterol-rich plasma membrane microdomains, referred to here as lipid rafts, serve as platforms for BCR signaling and trafficking in B cells. The existence of rafts suggests a previously unappreciated level of organization at the B cell surface that may explain, at least in part, how BCR signaling is coordinated. Here the current evidence that lipid rafts play a key role in B cell responses is reviewed." @default.
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- W2017265557 date "2001-04-01" @default.
- W2017265557 modified "2023-09-27" @default.
- W2017265557 title "Floating the raft hypothesis: the roles of lipid rafts in B cell antigen receptor function" @default.
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- W2017265557 doi "https://doi.org/10.1006/smim.2000.0302" @default.
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