FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017270902> ?p ?o ?g. }

• W2017270902 endingPage "444" @default.
• W2017270902 startingPage "436" @default.
• W2017270902 abstract "Mesenchymal stem cells (MSCs) have the ability to proliferate and differentiate into various lineages, given the appropriate microenvironment, thus making MSCs promising candidates for cell transplantation. For clinical applications, MSCs need to be stored in optimal conditions so that they may be transported and made available as an off-the-shelf product for companies to market. Freshly harvested and cultured or frozen-thawed bone marrow-derived MSCs were prepared for cell transplantation. Both freshly cultured or frozen-thawed MSCs were washed and resuspended in parenteral solutions, either 0.9% saline, Dulbecco's phosphate-buffered saline (DPBS), plasmalyte A or 5%dextrose and held for 2, 4, 6 and 8 h at 4 degrees C, 37 degrees C and RT (22 degrees C). The viability of the cells, differentiation capability and expression of cell surface markers were analysed. MSCs harvested from fresh cultures, resuspended in the parenteral solutions and maintained at 4 degrees C for 6 h showed more than 90% viability, and the viability was appreciably better when suspended in 5% dextrose at 4 degrees C for 8 h. In contrast, frozen-thawed cells can be held for a maximum of 2 h after thawing before losing their viability significantly below permissible limits for transplantation. We are reporting for the first time the effect of various parenteral solutions, holding times and temperatures on the viability and functionality of bone marrow-derived freshly cultured or frozen-thawed MSCs for transplantation. Our results suggested that freshly harvested MSCs can be held for 8 h at 4 degrees C in 5% dextrose or for up to 6 h at 4 degrees C in saline, DPBS or plasmalyte A. Freeze-thawed MSCs can be held for a maximum of 2 h in plasmalyte A before transplantation without affecting their viability and ability to differentiate." @default.
• W2017270902 created "2016-06-24" @default.
• W2017270902 creator A5009927391 @default.
• W2017270902 creator A5021011359 @default.
• W2017270902 creator A5088083791 @default.
• W2017270902 date "2008-10-01" @default.
• W2017270902 modified "2023-10-18" @default.
• W2017270902 title "Effect of holding time, temperature and different parenteral solutions on viability and functionality of adult bone marrow-derived mesenchymal stem cells before transplantation" @default.
• W2017270902 cites W1965953554 @default.
• W2017270902 cites W1966997376 @default.
• W2017270902 cites W1972171120 @default.
• W2017270902 cites W1982408656 @default.
• W2017270902 cites W1982561969 @default.
• W2017270902 cites W1996692762 @default.
• W2017270902 cites W2007110771 @default.
• W2017270902 cites W2042091279 @default.
• W2017270902 cites W2054727711 @default.
• W2017270902 cites W2061981400 @default.
• W2017270902 cites W2072386632 @default.
• W2017270902 cites W2080523658 @default.
• W2017270902 cites W2123402756 @default.
• W2017270902 cites W2141310245 @default.
• W2017270902 cites W2158048826 @default.
• W2017270902 cites W2159999899 @default.
• W2017270902 cites W4232584760 @default.
• W2017270902 cites W4243820570 @default.
• W2017270902 doi "https://doi.org/10.1002/term.109" @default.
• W2017270902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18720444" @default.
• W2017270902 hasPublicationYear "2008" @default.
• W2017270902 type Work @default.
• W2017270902 sameAs 2017270902 @default.
• W2017270902 citedByCount "70" @default.
• W2017270902 countsByYear W20172709022012 @default.
• W2017270902 countsByYear W20172709022013 @default.
• W2017270902 countsByYear W20172709022014 @default.
• W2017270902 countsByYear W20172709022015 @default.
• W2017270902 countsByYear W20172709022016 @default.
• W2017270902 countsByYear W20172709022017 @default.
• W2017270902 countsByYear W20172709022018 @default.
• W2017270902 countsByYear W20172709022019 @default.
• W2017270902 countsByYear W20172709022020 @default.
• W2017270902 countsByYear W20172709022021 @default.
• W2017270902 countsByYear W20172709022022 @default.
• W2017270902 countsByYear W20172709022023 @default.
• W2017270902 crossrefType "journal-article" @default.
• W2017270902 hasAuthorship W2017270902A5009927391 @default.
• W2017270902 hasAuthorship W2017270902A5021011359 @default.
• W2017270902 hasAuthorship W2017270902A5088083791 @default.
• W2017270902 hasBestOaLocation W20172709021 @default.
• W2017270902 hasConcept C126322002 @default.
• W2017270902 hasConcept C136229726 @default.
• W2017270902 hasConcept C141071460 @default.
• W2017270902 hasConcept C1491633281 @default.
• W2017270902 hasConcept C16685009 @default.
• W2017270902 hasConcept C185592680 @default.
• W2017270902 hasConcept C198826908 @default.
• W2017270902 hasConcept C203014093 @default.
• W2017270902 hasConcept C2777397205 @default.
• W2017270902 hasConcept C2780007613 @default.
• W2017270902 hasConcept C2911091166 @default.
• W2017270902 hasConcept C53227056 @default.
• W2017270902 hasConcept C55493867 @default.
• W2017270902 hasConcept C71924100 @default.
• W2017270902 hasConcept C86803240 @default.
• W2017270902 hasConcept C95444343 @default.
• W2017270902 hasConceptScore W2017270902C126322002 @default.
• W2017270902 hasConceptScore W2017270902C136229726 @default.
• W2017270902 hasConceptScore W2017270902C141071460 @default.
• W2017270902 hasConceptScore W2017270902C1491633281 @default.
• W2017270902 hasConceptScore W2017270902C16685009 @default.
• W2017270902 hasConceptScore W2017270902C185592680 @default.
• W2017270902 hasConceptScore W2017270902C198826908 @default.
• W2017270902 hasConceptScore W2017270902C203014093 @default.
• W2017270902 hasConceptScore W2017270902C2777397205 @default.
• W2017270902 hasConceptScore W2017270902C2780007613 @default.
• W2017270902 hasConceptScore W2017270902C2911091166 @default.
• W2017270902 hasConceptScore W2017270902C53227056 @default.
• W2017270902 hasConceptScore W2017270902C55493867 @default.
• W2017270902 hasConceptScore W2017270902C71924100 @default.
• W2017270902 hasConceptScore W2017270902C86803240 @default.
• W2017270902 hasConceptScore W2017270902C95444343 @default.
• W2017270902 hasIssue "7" @default.
• W2017270902 hasLocation W20172709021 @default.
• W2017270902 hasLocation W20172709022 @default.
• W2017270902 hasOpenAccess W2017270902 @default.
• W2017270902 hasPrimaryLocation W20172709021 @default.
• W2017270902 hasRelatedWork W1797702204 @default.
• W2017270902 hasRelatedWork W2464515224 @default.
• W2017270902 hasRelatedWork W2485516716 @default.
• W2017270902 hasRelatedWork W2756799244 @default.
• W2017270902 hasRelatedWork W2802557594 @default.
• W2017270902 hasRelatedWork W4224326768 @default.
• W2017270902 hasRelatedWork W4224737743 @default.
• W2017270902 hasRelatedWork W4376112202 @default.
• W2017270902 hasRelatedWork W4376112403 @default.
• W2017270902 hasRelatedWork W4376112453 @default.
• W2017270902 hasVolume "2" @default.
• W2017270902 isParatext "false" @default.

• next