Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017277531> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2017277531 endingPage "155" @default.
- W2017277531 startingPage "147" @default.
- W2017277531 abstract "A better understanding of the structure of complex 3H-labeled molecules can be obtained by complete assignment of their 1H and 3H solution-state NMR spectra. The assignment process is aided by the detection of heteronuclear chemical shift correlations between 1H and 3H nuclei. Heteronuclear correlation (HETCOR) experiments previously applied to this task exhibit several drawbacks caused by the nature of both the pulse sequences and 1H–3H spin systems. The range of J-couplings involved in 1H–3H coupling networks make it challenging to perform correlation experiments using methods that rely on coherences created during free precession periods and interrupted by transfer pulses. Two alternative HETCOR experiments are demonstrated for 1H–3H systems in the present work and are shown to have advantages over earlier methods. The first experiment is known as hetero-TOCSY and correlates heteronuclear chemical shifts using J-cross polarization. This experiment achieves both homonuclear and heteronuclear mixing and connects the chemical shifts of all 1H and 3H nuclei in a coupling network. A second HETCOR experiment uses the heteronuclear Overhauser effect to obtain through-space correlations between nearby nuclei. The 1H–3H HETCOR experiments are phase sensitive and typically contain more correlations than other methods, which is beneficial for assignment purposes, while being sensitive enough to be applicable to routine analytical samples. The experiments were used to analyze 3H incorporation in sub-milligram quantities of 3H-labeled pharmaceutical derivatives with complex labeling schemes. Copyright © 2004 John Wiley & Sons, Ltd." @default.
- W2017277531 created "2016-06-24" @default.
- W2017277531 creator A5006204318 @default.
- W2017277531 creator A5018092461 @default.
- W2017277531 creator A5048249468 @default.
- W2017277531 creator A5063072023 @default.
- W2017277531 creator A5067759314 @default.
- W2017277531 date "2005-01-01" @default.
- W2017277531 modified "2023-10-18" @default.
- W2017277531 title "Improved methods for1H-3H heteronuclear shift correlation" @default.
- W2017277531 cites W1964698321 @default.
- W2017277531 cites W1967320249 @default.
- W2017277531 cites W1975149801 @default.
- W2017277531 cites W1988315974 @default.
- W2017277531 cites W1994138154 @default.
- W2017277531 cites W1995627146 @default.
- W2017277531 cites W2004880376 @default.
- W2017277531 cites W2006577807 @default.
- W2017277531 cites W2015556833 @default.
- W2017277531 cites W2016903468 @default.
- W2017277531 cites W2022673999 @default.
- W2017277531 cites W2025000361 @default.
- W2017277531 cites W2029157942 @default.
- W2017277531 cites W2052154735 @default.
- W2017277531 cites W2059304082 @default.
- W2017277531 cites W2066186271 @default.
- W2017277531 cites W2067192674 @default.
- W2017277531 cites W2079079332 @default.
- W2017277531 cites W2083808580 @default.
- W2017277531 cites W2103220747 @default.
- W2017277531 cites W2117838041 @default.
- W2017277531 cites W2121906522 @default.
- W2017277531 cites W2140068608 @default.
- W2017277531 cites W1997321925 @default.
- W2017277531 doi "https://doi.org/10.1002/mrc.1518" @default.
- W2017277531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15593350" @default.
- W2017277531 hasPublicationYear "2005" @default.
- W2017277531 type Work @default.
- W2017277531 sameAs 2017277531 @default.
- W2017277531 citedByCount "1" @default.
- W2017277531 countsByYear W20172775312023 @default.
- W2017277531 crossrefType "journal-article" @default.
- W2017277531 hasAuthorship W2017277531A5006204318 @default.
- W2017277531 hasAuthorship W2017277531A5018092461 @default.
- W2017277531 hasAuthorship W2017277531A5048249468 @default.
- W2017277531 hasAuthorship W2017277531A5063072023 @default.
- W2017277531 hasAuthorship W2017277531A5067759314 @default.
- W2017277531 hasConcept C113196181 @default.
- W2017277531 hasConcept C119851462 @default.
- W2017277531 hasConcept C121332964 @default.
- W2017277531 hasConcept C178790620 @default.
- W2017277531 hasConcept C182155053 @default.
- W2017277531 hasConcept C185592680 @default.
- W2017277531 hasConcept C19549132 @default.
- W2017277531 hasConcept C32909587 @default.
- W2017277531 hasConcept C40447573 @default.
- W2017277531 hasConcept C43617362 @default.
- W2017277531 hasConcept C46141821 @default.
- W2017277531 hasConcept C66974803 @default.
- W2017277531 hasConcept C71240020 @default.
- W2017277531 hasConcept C92381491 @default.
- W2017277531 hasConceptScore W2017277531C113196181 @default.
- W2017277531 hasConceptScore W2017277531C119851462 @default.
- W2017277531 hasConceptScore W2017277531C121332964 @default.
- W2017277531 hasConceptScore W2017277531C178790620 @default.
- W2017277531 hasConceptScore W2017277531C182155053 @default.
- W2017277531 hasConceptScore W2017277531C185592680 @default.
- W2017277531 hasConceptScore W2017277531C19549132 @default.
- W2017277531 hasConceptScore W2017277531C32909587 @default.
- W2017277531 hasConceptScore W2017277531C40447573 @default.
- W2017277531 hasConceptScore W2017277531C43617362 @default.
- W2017277531 hasConceptScore W2017277531C46141821 @default.
- W2017277531 hasConceptScore W2017277531C66974803 @default.
- W2017277531 hasConceptScore W2017277531C71240020 @default.
- W2017277531 hasConceptScore W2017277531C92381491 @default.
- W2017277531 hasIssue "2" @default.
- W2017277531 hasLocation W20172775311 @default.
- W2017277531 hasLocation W20172775312 @default.
- W2017277531 hasOpenAccess W2017277531 @default.
- W2017277531 hasPrimaryLocation W20172775311 @default.
- W2017277531 hasRelatedWork W1995958671 @default.
- W2017277531 hasRelatedWork W2015104698 @default.
- W2017277531 hasRelatedWork W2037167408 @default.
- W2017277531 hasRelatedWork W2058773188 @default.
- W2017277531 hasRelatedWork W2070582492 @default.
- W2017277531 hasRelatedWork W2119581221 @default.
- W2017277531 hasRelatedWork W2581966282 @default.
- W2017277531 hasRelatedWork W2951571204 @default.
- W2017277531 hasRelatedWork W3116823915 @default.
- W2017277531 hasRelatedWork W629467513 @default.
- W2017277531 hasVolume "43" @default.
- W2017277531 isParatext "false" @default.
- W2017277531 isRetracted "false" @default.
- W2017277531 magId "2017277531" @default.
- W2017277531 workType "article" @default.