Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017281454> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2017281454 abstract "The eventual commonplace use of recombinant human erythropoietin (r-HuEPo) for the treatment of the anemia associated with chronic renal failure will have definite consequences in the dialysis supported patient. The effect of this nonanemic state on renal transplantation, both in the early posttransplant period as well as the waiting period, was examined in this study. Thirteen of 16 patients who were treated with the hormone and subsequently underwent cadaveric renal transplantation (Tx) were compared to control transplant patients from a typical chronic renal patient population. There seemed to be no difference in the length of hospital stay, need for dialysis support post-Tx, or severity of acute post-Tx renal failure as measured by the days of dialysis support given. Furthermore, there seemed to be no evidence of marrow unresponsiveness to endogenous erythropoietin produced by the functioning allograft, so that after an initial fall in hemoglobin and hematocrit, these parameters returned to normal levels at three to six months. HLA antibody production was also tracked over the course of chronic r-HuEPo therapy, and the response followed one of three patterns: (a) initially very high (100%) or very low (less than 15%) and showed no change; (b) moderate to high reactivity fell to lower levels with time; or (c) some stimulation noted without recent blood transfusions. Thus, patients entering end-stage renal failure without having been exposed to transfusions can be maintained in a low antibody state and perhaps increase the cadaveric kidneys available to them. Therefore, r-HuEPo therapy in patients who will subsequently undergo transplantation seems to have no deleterious effect on patient morbidity, or transplant outcome.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2017281454 created "2016-06-24" @default.
- W2017281454 creator A5003948100 @default.
- W2017281454 creator A5008432547 @default.
- W2017281454 creator A5063969126 @default.
- W2017281454 creator A5064600877 @default.
- W2017281454 date "1989-07-01" @default.
- W2017281454 modified "2023-09-24" @default.
- W2017281454 title "Renal Transplantation" @default.
- W2017281454 doi "https://doi.org/10.1097/00002216-198907000-00117" @default.
- W2017281454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2688720" @default.
- W2017281454 hasPublicationYear "1989" @default.
- W2017281454 type Work @default.
- W2017281454 sameAs 2017281454 @default.
- W2017281454 citedByCount "3" @default.
- W2017281454 countsByYear W20172814542017 @default.
- W2017281454 crossrefType "journal-article" @default.
- W2017281454 hasAuthorship W2017281454A5003948100 @default.
- W2017281454 hasAuthorship W2017281454A5008432547 @default.
- W2017281454 hasAuthorship W2017281454A5063969126 @default.
- W2017281454 hasAuthorship W2017281454A5064600877 @default.
- W2017281454 hasConcept C126322002 @default.
- W2017281454 hasConcept C126894567 @default.
- W2017281454 hasConcept C141071460 @default.
- W2017281454 hasConcept C2778248108 @default.
- W2017281454 hasConcept C2778534260 @default.
- W2017281454 hasConcept C2778917026 @default.
- W2017281454 hasConcept C2779978075 @default.
- W2017281454 hasConcept C2780303639 @default.
- W2017281454 hasConcept C2780959883 @default.
- W2017281454 hasConcept C2908647359 @default.
- W2017281454 hasConcept C2911091166 @default.
- W2017281454 hasConcept C2993356106 @default.
- W2017281454 hasConcept C71924100 @default.
- W2017281454 hasConcept C90924648 @default.
- W2017281454 hasConcept C99454951 @default.
- W2017281454 hasConceptScore W2017281454C126322002 @default.
- W2017281454 hasConceptScore W2017281454C126894567 @default.
- W2017281454 hasConceptScore W2017281454C141071460 @default.
- W2017281454 hasConceptScore W2017281454C2778248108 @default.
- W2017281454 hasConceptScore W2017281454C2778534260 @default.
- W2017281454 hasConceptScore W2017281454C2778917026 @default.
- W2017281454 hasConceptScore W2017281454C2779978075 @default.
- W2017281454 hasConceptScore W2017281454C2780303639 @default.
- W2017281454 hasConceptScore W2017281454C2780959883 @default.
- W2017281454 hasConceptScore W2017281454C2908647359 @default.
- W2017281454 hasConceptScore W2017281454C2911091166 @default.
- W2017281454 hasConceptScore W2017281454C2993356106 @default.
- W2017281454 hasConceptScore W2017281454C71924100 @default.
- W2017281454 hasConceptScore W2017281454C90924648 @default.
- W2017281454 hasConceptScore W2017281454C99454951 @default.
- W2017281454 hasLocation W20172814541 @default.
- W2017281454 hasLocation W20172814542 @default.
- W2017281454 hasOpenAccess W2017281454 @default.
- W2017281454 hasPrimaryLocation W20172814541 @default.
- W2017281454 hasRelatedWork W2017281454 @default.
- W2017281454 hasRelatedWork W2068881202 @default.
- W2017281454 hasRelatedWork W2158399804 @default.
- W2017281454 hasRelatedWork W2361108265 @default.
- W2017281454 hasRelatedWork W2375101873 @default.
- W2017281454 hasRelatedWork W2386058477 @default.
- W2017281454 hasRelatedWork W2390387684 @default.
- W2017281454 hasRelatedWork W2412425337 @default.
- W2017281454 hasRelatedWork W2415599063 @default.
- W2017281454 hasRelatedWork W2805683016 @default.
- W2017281454 isParatext "false" @default.
- W2017281454 isRetracted "false" @default.
- W2017281454 magId "2017281454" @default.
- W2017281454 workType "article" @default.