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- W2017282255 abstract "A single nucleotide polymorphism (SNP) −420C > G of the resistin gene was screened in 248 colorectal cancer (CRC) patients and 256 controls. No significant difference in genotype distribution was found. However, we found an upregulation in 92% of the samples in the levels of resistin protein in cancer tissue (n = 83). Immunohistochemical analysis revealed heterogenous staining of resistin predominantly in the cancer tissue. Further, resistin induced secretion of MMP-2 and MMP-9 from monocytes. The results of this study suggest that resistin may play a partial role in CRC but that the −420C > G resistin polymorphism is not a potential genetic susceptibility factor." @default.
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- W2017282255 date "2008-01-01" @default.
- W2017282255 modified "2023-10-18" @default.
- W2017282255 title "Resistin in Human Colorectal Cancer: Increased Expression Independently of Resistin Promoter −420C > G genotype" @default.
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- W2017282255 doi "https://doi.org/10.1080/07357900802087267" @default.
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