FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017283710> ?p ?o ?g. }

• W2017283710 endingPage "e95991" @default.
• W2017283710 startingPage "e95991" @default.
• W2017283710 abstract "Background Adverse drug reactions (ADRs) represent a major burden on the healthcare system. Chronic kidney disease (CKD) patients are particularly vulnerable to ADRs because they are usually on multiple drug regimens, have multiple comorbidities, and because of alteration in their pharmacokinetics and pharmacodynamic parameters. Therefore, one step towards reducing this burden is to identify patients who are at increased risk of an ADR. Objective To develop a method of identifying CKD patients who are at increased risk for experiencing ADRs during hospitalisation. Materials and Methods Factors associated with ADRs were identified by using demographic, clinical and laboratory variables of patients with CKD stages 3 to 5 (estimated glomerular filtration rate, 10–59 ml/min/1.73 m2) who were admitted between January 1, 2012, and December 31, 2012, to the renal unit of Dubai Hospital. An ADR risk score was developed by constructing a series of logistic regression models. The overall model performance for sequential models was evaluated using Akaike Information Criterion for goodness of fit. Odd ratios of the variables retained in the best model were used to compute the risk scores. Results Of 512 patients (mean [SD] age, 60 [16] years), 62 (12.1%) experienced an ADR during their hospitalisation. An ADR risk score included age 65 years or more, female sex, conservatively managed end-stage renal disease, vascular disease, serum level of C-reactive protein more than 10 mg/L, serum level of albumin less than 3.5 g/dL, and the use of 8 medications or more during hospitalization. The C statistic, which assesses the ability of the risk score to predict ADRs, was 0.838; 95% CI, 0.784–0.892). Conclusion A score using routinely available patient data can be used to identify CKD patients who are at increased risk of ADRs." @default.
• W2017283710 created "2016-06-24" @default.
• W2017283710 creator A5016305675 @default.
• W2017283710 creator A5037633205 @default.
• W2017283710 creator A5055788175 @default.
• W2017283710 creator A5073020673 @default.
• W2017283710 date "2014-04-22" @default.
• W2017283710 modified "2023-09-27" @default.
• W2017283710 title "Development of an Adverse Drug Reaction Risk Assessment Score among Hospitalized Patients with Chronic Kidney Disease" @default.
• W2017283710 cites W1570583414 @default.
• W2017283710 cites W1969879564 @default.
• W2017283710 cites W1979758037 @default.
• W2017283710 cites W1992746042 @default.
• W2017283710 cites W2001299659 @default.
• W2017283710 cites W2001511735 @default.
• W2017283710 cites W2019300001 @default.
• W2017283710 cites W2021101440 @default.
• W2017283710 cites W2025395978 @default.
• W2017283710 cites W2030060276 @default.
• W2017283710 cites W2034690624 @default.
• W2017283710 cites W2034981842 @default.
• W2017283710 cites W2051428761 @default.
• W2017283710 cites W2055864845 @default.
• W2017283710 cites W2067978628 @default.
• W2017283710 cites W2074932800 @default.
• W2017283710 cites W2075455619 @default.
• W2017283710 cites W2080995941 @default.
• W2017283710 cites W2088028867 @default.
• W2017283710 cites W2092385611 @default.
• W2017283710 cites W2094479361 @default.
• W2017283710 cites W2095713539 @default.
• W2017283710 cites W2107250597 @default.
• W2017283710 cites W2112316706 @default.
• W2017283710 cites W2119910794 @default.
• W2017283710 cites W2121055261 @default.
• W2017283710 cites W2124994058 @default.
• W2017283710 cites W2130373985 @default.
• W2017283710 cites W2133948398 @default.
• W2017283710 cites W2153972688 @default.
• W2017283710 cites W2167222607 @default.
• W2017283710 cites W2167601673 @default.
• W2017283710 cites W2171632408 @default.
• W2017283710 cites W2266995761 @default.
• W2017283710 cites W3106889297 @default.
• W2017283710 cites W4213286494 @default.
• W2017283710 cites W4229956755 @default.
• W2017283710 doi "https://doi.org/10.1371/journal.pone.0095991" @default.
• W2017283710 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3995995" @default.
• W2017283710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24755778" @default.
• W2017283710 hasPublicationYear "2014" @default.
• W2017283710 type Work @default.
• W2017283710 sameAs 2017283710 @default.
• W2017283710 citedByCount "29" @default.
• W2017283710 countsByYear W20172837102014 @default.
• W2017283710 countsByYear W20172837102015 @default.
• W2017283710 countsByYear W20172837102016 @default.
• W2017283710 countsByYear W20172837102017 @default.
• W2017283710 countsByYear W20172837102018 @default.
• W2017283710 countsByYear W20172837102019 @default.
• W2017283710 countsByYear W20172837102020 @default.
• W2017283710 countsByYear W20172837102021 @default.
• W2017283710 countsByYear W20172837102022 @default.
• W2017283710 countsByYear W20172837102023 @default.
• W2017283710 crossrefType "journal-article" @default.
• W2017283710 hasAuthorship W2017283710A5016305675 @default.
• W2017283710 hasAuthorship W2017283710A5037633205 @default.
• W2017283710 hasAuthorship W2017283710A5055788175 @default.
• W2017283710 hasAuthorship W2017283710A5073020673 @default.
• W2017283710 hasBestOaLocation W20172837101 @default.
• W2017283710 hasConcept C105795698 @default.
• W2017283710 hasConcept C126322002 @default.
• W2017283710 hasConcept C126674687 @default.
• W2017283710 hasConcept C151956035 @default.
• W2017283710 hasConcept C159641895 @default.
• W2017283710 hasConcept C177713679 @default.
• W2017283710 hasConcept C197934379 @default.
• W2017283710 hasConcept C2778653478 @default.
• W2017283710 hasConcept C2779134260 @default.
• W2017283710 hasConcept C2780035454 @default.
• W2017283710 hasConcept C33923547 @default.
• W2017283710 hasConcept C71924100 @default.
• W2017283710 hasConcept C98274493 @default.
• W2017283710 hasConceptScore W2017283710C105795698 @default.
• W2017283710 hasConceptScore W2017283710C126322002 @default.
• W2017283710 hasConceptScore W2017283710C126674687 @default.
• W2017283710 hasConceptScore W2017283710C151956035 @default.
• W2017283710 hasConceptScore W2017283710C159641895 @default.
• W2017283710 hasConceptScore W2017283710C177713679 @default.
• W2017283710 hasConceptScore W2017283710C197934379 @default.
• W2017283710 hasConceptScore W2017283710C2778653478 @default.
• W2017283710 hasConceptScore W2017283710C2779134260 @default.
• W2017283710 hasConceptScore W2017283710C2780035454 @default.
• W2017283710 hasConceptScore W2017283710C33923547 @default.
• W2017283710 hasConceptScore W2017283710C71924100 @default.
• W2017283710 hasConceptScore W2017283710C98274493 @default.
• W2017283710 hasIssue "4" @default.
• W2017283710 hasLocation W20172837101 @default.
• W2017283710 hasLocation W20172837102 @default.

• next