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- W2017288049 abstract "We present the case of a patient with a cobalamin deficiency resulting in pancytopaenia, emphasizing the importance to define, diagnose and treat cobalamin deficiency.A 52-year-old man from the Democratic Republic of Congo presented to the emergency department with shortness of breath and a sore tongue. Physical examination was unremarkable. His haemoglobin was low and the peripheral blood smear revealed pancytopaenia with a thrombotic microangiopathy. The findings were low cobalamin and folate levels, and high homocysteine and methylmalonate levels. Pernicious anaemia with chronic atrophic gastritis was confirmed by gastric biopsy and positive antiparietal cell and anti-intrinsic factor antibodies. Cobalamin with added folate was given. Six months later, the patient was asymptomatic.Cobalamin deficiency should always be ruled out in a patient with pancytopaenia. Our case report highlights a life-threatening cobalamin deficiency completely reversible after treatment." @default.
- W2017288049 created "2016-06-24" @default.
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- W2017288049 date "2009-10-20" @default.
- W2017288049 modified "2023-09-26" @default.
- W2017288049 title "Cobalamin deficiency resulting in a rare haematological disorder: a case report" @default.
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- W2017288049 doi "https://doi.org/10.1186/1752-1947-3-80" @default.
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