FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017288974> ?p ?o ?g. }

• W2017288974 endingPage "846" @default.
• W2017288974 startingPage "841" @default.
• W2017288974 abstract "<b><i>Background: </i></b> The mechanisms underlying altered consciousness during seizures are poorly understood. Previous clinicopathologic studies suggest a role for the thalamus and upper brainstem in consciousness mechanisms. <b><i>Objective:</i></b> To examine blood flow changes associated with altered consciousness during seizures. <b><i>Methods: </i></b> Seventy-one patients with epilepsy who underwent video-EEG monitoring and ictal/interictal SPECT were studied. Patients were divided into three groups depending on their conscious state during seizures: 1) complete impairment of consciousness (CI), 2) no impairment of consciousness (NI), or 3) uncertain impairment of consciousness (UI). The distribution of blood flow changes during these seizures was assessed by subtraction (ictal − interictal) SPECT co-registered to MRI. Conscious state was assessed in relation to secondary ictal hyperperfusion in subcortical regions (i.e., thalamus and upper brainstem). <b><i>Results: </i></b> Impairment of consciousness showed a strong association with secondary hyperperfusion in the thalamic/upper brainstem region (<i>p</i> = 0.01), occurring in 92% (45/49) of CI, 69% (9/13) of UI, and 11% (1/9) of NI. <b><i>Conclusions: </i></b> These findings are consistent with a role for the thalamus and upper brainstem in consciousness mechanisms. The authors suggest that the spread of epileptic discharges or a trans-synaptic activation (diaschisis) of these structures is an important mechanism in the alteration of consciousness during seizures. Variance in the results may be due to differences in timing of radioisotope injection, sensitivity of the subtraction SPECT technique, and the ability to clinically assess the conscious state." @default.
• W2017288974 created "2016-06-24" @default.
• W2017288974 creator A5028468371 @default.
• W2017288974 creator A5028839905 @default.
• W2017288974 creator A5052042957 @default.
• W2017288974 creator A5062406099 @default.
• W2017288974 creator A5079648368 @default.
• W2017288974 creator A5081563026 @default.
• W2017288974 creator A5086929815 @default.
• W2017288974 date "2002-09-24" @default.
• W2017288974 modified "2023-09-23" @default.
• W2017288974 title "Pathophysiology of altered consciousness during seizures: Subtraction SPECT study" @default.
• W2017288974 cites W1523826181 @default.
• W2017288974 cites W1985716571 @default.
• W2017288974 cites W2005015525 @default.
• W2017288974 cites W2021661569 @default.
• W2017288974 cites W2023689236 @default.
• W2017288974 cites W2025687973 @default.
• W2017288974 cites W2036859913 @default.
• W2017288974 cites W2040170845 @default.
• W2017288974 cites W2043158507 @default.
• W2017288974 cites W2062649574 @default.
• W2017288974 cites W2066284558 @default.
• W2017288974 cites W2082505653 @default.
• W2017288974 cites W2124025293 @default.
• W2017288974 cites W2129378181 @default.
• W2017288974 cites W2147200751 @default.
• W2017288974 cites W2162575572 @default.
• W2017288974 cites W2419045361 @default.
• W2017288974 doi "https://doi.org/10.1212/wnl.59.6.841" @default.
• W2017288974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12297563" @default.
• W2017288974 hasPublicationYear "2002" @default.
• W2017288974 type Work @default.
• W2017288974 sameAs 2017288974 @default.
• W2017288974 citedByCount "91" @default.
• W2017288974 countsByYear W20172889742012 @default.
• W2017288974 countsByYear W20172889742013 @default.
• W2017288974 countsByYear W20172889742014 @default.
• W2017288974 countsByYear W20172889742015 @default.
• W2017288974 countsByYear W20172889742016 @default.
• W2017288974 countsByYear W20172889742017 @default.
• W2017288974 countsByYear W20172889742018 @default.
• W2017288974 countsByYear W20172889742019 @default.
• W2017288974 countsByYear W20172889742020 @default.
• W2017288974 countsByYear W20172889742021 @default.
• W2017288974 countsByYear W20172889742022 @default.
• W2017288974 crossrefType "journal-article" @default.
• W2017288974 hasAuthorship W2017288974A5028468371 @default.
• W2017288974 hasAuthorship W2017288974A5028839905 @default.
• W2017288974 hasAuthorship W2017288974A5052042957 @default.
• W2017288974 hasAuthorship W2017288974A5062406099 @default.
• W2017288974 hasAuthorship W2017288974A5079648368 @default.
• W2017288974 hasAuthorship W2017288974A5081563026 @default.
• W2017288974 hasAuthorship W2017288974A5086929815 @default.
• W2017288974 hasConcept C15744967 @default.
• W2017288974 hasConcept C169760540 @default.
• W2017288974 hasConcept C171525899 @default.
• W2017288974 hasConcept C17755696 @default.
• W2017288974 hasConcept C186720457 @default.
• W2017288974 hasConcept C2778186239 @default.
• W2017288974 hasConcept C2779246727 @default.
• W2017288974 hasConcept C2779281540 @default.
• W2017288974 hasConcept C33923547 @default.
• W2017288974 hasConcept C42219234 @default.
• W2017288974 hasConcept C522805319 @default.
• W2017288974 hasConcept C551621295 @default.
• W2017288974 hasConcept C68060419 @default.
• W2017288974 hasConcept C71924100 @default.
• W2017288974 hasConcept C94375191 @default.
• W2017288974 hasConceptScore W2017288974C15744967 @default.
• W2017288974 hasConceptScore W2017288974C169760540 @default.
• W2017288974 hasConceptScore W2017288974C171525899 @default.
• W2017288974 hasConceptScore W2017288974C17755696 @default.
• W2017288974 hasConceptScore W2017288974C186720457 @default.
• W2017288974 hasConceptScore W2017288974C2778186239 @default.
• W2017288974 hasConceptScore W2017288974C2779246727 @default.
• W2017288974 hasConceptScore W2017288974C2779281540 @default.
• W2017288974 hasConceptScore W2017288974C33923547 @default.
• W2017288974 hasConceptScore W2017288974C42219234 @default.
• W2017288974 hasConceptScore W2017288974C522805319 @default.
• W2017288974 hasConceptScore W2017288974C551621295 @default.
• W2017288974 hasConceptScore W2017288974C68060419 @default.
• W2017288974 hasConceptScore W2017288974C71924100 @default.
• W2017288974 hasConceptScore W2017288974C94375191 @default.
• W2017288974 hasIssue "6" @default.
• W2017288974 hasLocation W20172889741 @default.
• W2017288974 hasLocation W20172889742 @default.
• W2017288974 hasOpenAccess W2017288974 @default.
• W2017288974 hasPrimaryLocation W20172889741 @default.
• W2017288974 hasRelatedWork W1990627463 @default.
• W2017288974 hasRelatedWork W2008631356 @default.
• W2017288974 hasRelatedWork W2010143137 @default.
• W2017288974 hasRelatedWork W2016645643 @default.
• W2017288974 hasRelatedWork W2017288974 @default.
• W2017288974 hasRelatedWork W2087401364 @default.
• W2017288974 hasRelatedWork W2152120467 @default.
• W2017288974 hasRelatedWork W2168763307 @default.
• W2017288974 hasRelatedWork W3104061430 @default.

• next