FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017295331> ?p ?o ?g. }

• W2017295331 endingPage "5" @default.
• W2017295331 startingPage "1" @default.
• W2017295331 abstract "O,O,S-Trimethylphosphorothioate (OOS-TMP) has been shown to induce hypophagia and hypopraxia. Recent studies suggest that OOS-TMP-induced anorexia is partly mediated by its effect on the central nervous system. In this study, we examined the profiles of N-acylethanolamines (NEAs), including five amide-linked compounds, in the gastrointestinal system in C57BL/6J (B6) mice. The present results shown an orexigenic profile of the levels of NEAs with downregulation of the anorectic lipid, N-stearoylethanolamine (SEA), upregulation of the orexigenic lipid, 2-arachidonoyl glycerol (2-AG), at 2 h and upregulation of 2-AG at 24 h albeit with significant anorexia. However, the data indicated that the high level of 2-AG may be responsible for the hypopraxia. We next explored whether OOS-TMP may affect two models of hyperphagia and hyperglycemia, ins2(+/Akita) B6 (Akita) and B6-lepr(db)/lepr(db) mice (db/db). We identified potential anorexigenic effects in B6, Akita and db/db mice. Moreover, OOS-TMP was found to reduce blood glucose in Akita mice but not in db/db mice. Collectively, these findings suggest that N-acylethanolamines are not involved in the hypophagia but rather hypopraxia, and may play multiple physiological roles in this process. OOS-TMP might be a promising candidate for anti-obesity and anti-diabetic drug development." @default.
• W2017295331 created "2016-06-24" @default.
• W2017295331 creator A5007384237 @default.
• W2017295331 creator A5010596801 @default.
• W2017295331 creator A5016677481 @default.
• W2017295331 creator A5016782315 @default.
• W2017295331 creator A5049632995 @default.
• W2017295331 creator A5053307487 @default.
• W2017295331 creator A5070024796 @default.
• W2017295331 creator A5073635829 @default.
• W2017295331 date "2009-03-01" @default.
• W2017295331 modified "2023-10-14" @default.
• W2017295331 title "Levels of N-acylethanolamines in O,O,S-trimethylphosphorothioate (OOS-TMP)-treated C57BL/6J mice and potential anti-obesity, anti-diabetic effects of OOS-TMP in hyperphagia and hyperglycemia mouse models" @default.
• W2017295331 cites W1561443084 @default.
• W2017295331 cites W1963482720 @default.
• W2017295331 cites W1969657888 @default.
• W2017295331 cites W1973715121 @default.
• W2017295331 cites W1975060221 @default.
• W2017295331 cites W1975807625 @default.
• W2017295331 cites W1981250920 @default.
• W2017295331 cites W1986214624 @default.
• W2017295331 cites W1986836799 @default.
• W2017295331 cites W1993559798 @default.
• W2017295331 cites W1998679866 @default.
• W2017295331 cites W2014261817 @default.
• W2017295331 cites W2016360465 @default.
• W2017295331 cites W2016808790 @default.
• W2017295331 cites W2020053653 @default.
• W2017295331 cites W2024589245 @default.
• W2017295331 cites W2024653583 @default.
• W2017295331 cites W2031071131 @default.
• W2017295331 cites W2037224101 @default.
• W2017295331 cites W2058041563 @default.
• W2017295331 cites W2058940136 @default.
• W2017295331 cites W2073734463 @default.
• W2017295331 cites W2085741941 @default.
• W2017295331 cites W2089052356 @default.
• W2017295331 cites W2097705715 @default.
• W2017295331 cites W2106427201 @default.
• W2017295331 cites W2112924959 @default.
• W2017295331 cites W2119826244 @default.
• W2017295331 cites W2148821027 @default.
• W2017295331 cites W2151612123 @default.
• W2017295331 cites W2153836184 @default.
• W2017295331 cites W2154861643 @default.
• W2017295331 cites W2162112945 @default.
• W2017295331 cites W2163315694 @default.
• W2017295331 cites W331819613 @default.
• W2017295331 cites W4231471615 @default.
• W2017295331 doi "https://doi.org/10.1016/j.pbb.2008.10.003" @default.
• W2017295331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18992273" @default.
• W2017295331 hasPublicationYear "2009" @default.
• W2017295331 type Work @default.
• W2017295331 sameAs 2017295331 @default.
• W2017295331 citedByCount "2" @default.
• W2017295331 countsByYear W20172953312018 @default.
• W2017295331 crossrefType "journal-article" @default.
• W2017295331 hasAuthorship W2017295331A5007384237 @default.
• W2017295331 hasAuthorship W2017295331A5010596801 @default.
• W2017295331 hasAuthorship W2017295331A5016677481 @default.
• W2017295331 hasAuthorship W2017295331A5016782315 @default.
• W2017295331 hasAuthorship W2017295331A5049632995 @default.
• W2017295331 hasAuthorship W2017295331A5053307487 @default.
• W2017295331 hasAuthorship W2017295331A5070024796 @default.
• W2017295331 hasAuthorship W2017295331A5073635829 @default.
• W2017295331 hasConcept C104317684 @default.
• W2017295331 hasConcept C118303440 @default.
• W2017295331 hasConcept C126322002 @default.
• W2017295331 hasConcept C127561419 @default.
• W2017295331 hasConcept C134018914 @default.
• W2017295331 hasConcept C147583825 @default.
• W2017295331 hasConcept C170493617 @default.
• W2017295331 hasConcept C185592680 @default.
• W2017295331 hasConcept C2777003273 @default.
• W2017295331 hasConcept C2777205416 @default.
• W2017295331 hasConcept C2777369949 @default.
• W2017295331 hasConcept C2909274461 @default.
• W2017295331 hasConcept C55493867 @default.
• W2017295331 hasConcept C71924100 @default.
• W2017295331 hasConcept C93984277 @default.
• W2017295331 hasConceptScore W2017295331C104317684 @default.
• W2017295331 hasConceptScore W2017295331C118303440 @default.
• W2017295331 hasConceptScore W2017295331C126322002 @default.
• W2017295331 hasConceptScore W2017295331C127561419 @default.
• W2017295331 hasConceptScore W2017295331C134018914 @default.
• W2017295331 hasConceptScore W2017295331C147583825 @default.
• W2017295331 hasConceptScore W2017295331C170493617 @default.
• W2017295331 hasConceptScore W2017295331C185592680 @default.
• W2017295331 hasConceptScore W2017295331C2777003273 @default.
• W2017295331 hasConceptScore W2017295331C2777205416 @default.
• W2017295331 hasConceptScore W2017295331C2777369949 @default.
• W2017295331 hasConceptScore W2017295331C2909274461 @default.
• W2017295331 hasConceptScore W2017295331C55493867 @default.
• W2017295331 hasConceptScore W2017295331C71924100 @default.
• W2017295331 hasConceptScore W2017295331C93984277 @default.
• W2017295331 hasIssue "1" @default.
• W2017295331 hasLocation W20172953311 @default.
• W2017295331 hasLocation W20172953312 @default.

• next