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- W2017297130 abstract "Novel doubly branched apio dideoxynucleosides were synthesized starting from 1,3-dihydroxyacetone using an ozonolysis and Grignard addition as key steps, and evaluated for anti-hepatitis C virus (HCV) activity. The adenine derivative 24 showed significant anti-HCV activity, indicating that the branches at the 4',5'-position of the apiosyl ring led to favorable interaction with HCV polymerase." @default.
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- W2017297130 date "2009-12-07" @default.
- W2017297130 modified "2023-09-22" @default.
- W2017297130 title "Synthesis and In Vitro Activity of 4′ and 5′-Modified Analogues of Apiosyl Nucleosides as Potent Anti-HCV Agents" @default.
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- W2017297130 doi "https://doi.org/10.1080/15257770903396725" @default.
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