FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017303732> ?p ?o ?g. }

• W2017303732 abstract "AbstractDoxorubicin is the cornerstone of some widely used combination chemotherapy regimens because of its high anticancer activity in a number of human neoplasms. However, its clinical use is highly compromised because of treatment-limiting acute and chronic toxicities of which cardiotoxicity has the most debilitating effect. Our laboratories have demonstrated that liposome encapsulated doxorubicin (LED) provides important advantages in regards to the attenuation of cardiotoxicity in rodents by altering pharmacokinetics and pharmacodynamics of the drug, provides effective protection from immunotoxicity and maintains full therapeutic activity of the drug in liposomes. A Phase I clinical trial of LED in cancer patients has establish the maximum tolerated dose of 90 mg/m2 with granulocytopenia being the major treatment-limiting toxicity. We have performed a Phase II trial of LED in 20 recurrent breast cancer patients at a dose of 75 mg/m2 as an intravenous infusion every three weeks. Objective responses we..." @default.
• W2017303732 created "2016-06-24" @default.
• W2017303732 creator A5052787538 @default.
• W2017303732 creator A5061100035 @default.
• W2017303732 creator A5071648735 @default.
• W2017303732 creator A5081807758 @default.
• W2017303732 creator A5088629839 @default.
• W2017303732 date "1994-01-01" @default.
• W2017303732 modified "2023-09-28" @default.
• W2017303732 title "Clinical Evaluation of Liposome Encapsulated Doxorubicin and the Modulation of Multidrug Resistance in Cancer Cells" @default.
• W2017303732 cites W1528514916 @default.
• W2017303732 cites W1539939143 @default.
• W2017303732 cites W1544973014 @default.
• W2017303732 cites W1566526521 @default.
• W2017303732 cites W1596439003 @default.
• W2017303732 cites W1775749144 @default.
• W2017303732 cites W1819818791 @default.
• W2017303732 cites W1967688094 @default.
• W2017303732 cites W1977105311 @default.
• W2017303732 cites W1980360807 @default.
• W2017303732 cites W1986981812 @default.
• W2017303732 cites W1988382716 @default.
• W2017303732 cites W198917760 @default.
• W2017303732 cites W1992786087 @default.
• W2017303732 cites W1997241897 @default.
• W2017303732 cites W1998773179 @default.
• W2017303732 cites W2005890366 @default.
• W2017303732 cites W2007718340 @default.
• W2017303732 cites W2010590441 @default.
• W2017303732 cites W2013070978 @default.
• W2017303732 cites W2013541526 @default.
• W2017303732 cites W20139559 @default.
• W2017303732 cites W2024013564 @default.
• W2017303732 cites W2025639667 @default.
• W2017303732 cites W2026516892 @default.
• W2017303732 cites W2039642936 @default.
• W2017303732 cites W2050202061 @default.
• W2017303732 cites W2058563509 @default.
• W2017303732 cites W2071886602 @default.
• W2017303732 cites W2073636635 @default.
• W2017303732 cites W2079088649 @default.
• W2017303732 cites W2093442802 @default.
• W2017303732 cites W2097878215 @default.
• W2017303732 cites W2103970111 @default.
• W2017303732 cites W2111426313 @default.
• W2017303732 cites W2140323094 @default.
• W2017303732 cites W2325508287 @default.
• W2017303732 cites W2325872510 @default.
• W2017303732 cites W2434473292 @default.
• W2017303732 doi "https://doi.org/10.3109/08982109409037035" @default.
• W2017303732 hasPublicationYear "1994" @default.
• W2017303732 type Work @default.
• W2017303732 sameAs 2017303732 @default.
• W2017303732 citedByCount "3" @default.
• W2017303732 crossrefType "journal-article" @default.
• W2017303732 hasAuthorship W2017303732A5052787538 @default.
• W2017303732 hasAuthorship W2017303732A5061100035 @default.
• W2017303732 hasAuthorship W2017303732A5071648735 @default.
• W2017303732 hasAuthorship W2017303732A5081807758 @default.
• W2017303732 hasAuthorship W2017303732A5088629839 @default.
• W2017303732 hasConcept C111113717 @default.
• W2017303732 hasConcept C112705442 @default.
• W2017303732 hasConcept C114851261 @default.
• W2017303732 hasConcept C121608353 @default.
• W2017303732 hasConcept C126322002 @default.
• W2017303732 hasConcept C133936738 @default.
• W2017303732 hasConcept C171250308 @default.
• W2017303732 hasConcept C185154212 @default.
• W2017303732 hasConcept C192562407 @default.
• W2017303732 hasConcept C2776694085 @default.
• W2017303732 hasConcept C2778233292 @default.
• W2017303732 hasConcept C2780035454 @default.
• W2017303732 hasConcept C2781303535 @default.
• W2017303732 hasConcept C29730261 @default.
• W2017303732 hasConcept C535046627 @default.
• W2017303732 hasConcept C71924100 @default.
• W2017303732 hasConcept C86803240 @default.
• W2017303732 hasConcept C89423630 @default.
• W2017303732 hasConcept C98274493 @default.
• W2017303732 hasConceptScore W2017303732C111113717 @default.
• W2017303732 hasConceptScore W2017303732C112705442 @default.
• W2017303732 hasConceptScore W2017303732C114851261 @default.
• W2017303732 hasConceptScore W2017303732C121608353 @default.
• W2017303732 hasConceptScore W2017303732C126322002 @default.
• W2017303732 hasConceptScore W2017303732C133936738 @default.
• W2017303732 hasConceptScore W2017303732C171250308 @default.
• W2017303732 hasConceptScore W2017303732C185154212 @default.
• W2017303732 hasConceptScore W2017303732C192562407 @default.
• W2017303732 hasConceptScore W2017303732C2776694085 @default.
• W2017303732 hasConceptScore W2017303732C2778233292 @default.
• W2017303732 hasConceptScore W2017303732C2780035454 @default.
• W2017303732 hasConceptScore W2017303732C2781303535 @default.
• W2017303732 hasConceptScore W2017303732C29730261 @default.
• W2017303732 hasConceptScore W2017303732C535046627 @default.
• W2017303732 hasConceptScore W2017303732C71924100 @default.
• W2017303732 hasConceptScore W2017303732C86803240 @default.
• W2017303732 hasConceptScore W2017303732C89423630 @default.
• W2017303732 hasConceptScore W2017303732C98274493 @default.
• W2017303732 hasLocation W20173037321 @default.
• W2017303732 hasOpenAccess W2017303732 @default.

• next