Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017307812> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2017307812 abstract "A series of novel indolylpiperidine derivatives were synthesized, and their pharmacological profiles were assessed at rat α1A and α1B adrenoceptors through in vitro binding studies. Compound 12 (2-(3-(4-(6-fluoro-1H-indol-3-yl)piperidin-1-yl)propyl)-1,2,3,4-tetrahydroisoquinoline) was a potent α1B adrenoceptor antagonist (Ki=0.61 nM) and was about 40-fold more selective for the α1B adrenoceptor than for the α1A adrenoceptor. In addition, useful structure-activity relationship information was acquired for further improving selectivity for the α1B adrenoceptor." @default.
- W2017307812 created "2016-06-24" @default.
- W2017307812 creator A5052593052 @default.
- W2017307812 creator A5052673213 @default.
- W2017307812 creator A5057527260 @default.
- W2017307812 creator A5061277803 @default.
- W2017307812 creator A5068502700 @default.
- W2017307812 date "2015-09-01" @default.
- W2017307812 modified "2023-09-27" @default.
- W2017307812 title "Indolylpiperidine derivatives as potent and selective α1B adrenoceptor antagonists" @default.
- W2017307812 cites W1581652555 @default.
- W2017307812 cites W1970723337 @default.
- W2017307812 cites W1981135552 @default.
- W2017307812 cites W1982577072 @default.
- W2017307812 cites W1982657636 @default.
- W2017307812 cites W2016891517 @default.
- W2017307812 cites W2082201094 @default.
- W2017307812 cites W2085777592 @default.
- W2017307812 cites W2125685489 @default.
- W2017307812 cites W2158109323 @default.
- W2017307812 cites W2273864730 @default.
- W2017307812 cites W2411799202 @default.
- W2017307812 doi "https://doi.org/10.1016/j.bmcl.2015.07.046" @default.
- W2017307812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26238322" @default.
- W2017307812 hasPublicationYear "2015" @default.
- W2017307812 type Work @default.
- W2017307812 sameAs 2017307812 @default.
- W2017307812 citedByCount "0" @default.
- W2017307812 crossrefType "journal-article" @default.
- W2017307812 hasAuthorship W2017307812A5052593052 @default.
- W2017307812 hasAuthorship W2017307812A5052673213 @default.
- W2017307812 hasAuthorship W2017307812A5057527260 @default.
- W2017307812 hasAuthorship W2017307812A5061277803 @default.
- W2017307812 hasAuthorship W2017307812A5068502700 @default.
- W2017307812 hasConcept C114373084 @default.
- W2017307812 hasConcept C118792377 @default.
- W2017307812 hasConcept C161790260 @default.
- W2017307812 hasConcept C170493617 @default.
- W2017307812 hasConcept C185592680 @default.
- W2017307812 hasConcept C193042331 @default.
- W2017307812 hasConcept C202751555 @default.
- W2017307812 hasConcept C2776885963 @default.
- W2017307812 hasConcept C55493867 @default.
- W2017307812 hasConcept C71240020 @default.
- W2017307812 hasConcept C71924100 @default.
- W2017307812 hasConcept C98274493 @default.
- W2017307812 hasConceptScore W2017307812C114373084 @default.
- W2017307812 hasConceptScore W2017307812C118792377 @default.
- W2017307812 hasConceptScore W2017307812C161790260 @default.
- W2017307812 hasConceptScore W2017307812C170493617 @default.
- W2017307812 hasConceptScore W2017307812C185592680 @default.
- W2017307812 hasConceptScore W2017307812C193042331 @default.
- W2017307812 hasConceptScore W2017307812C202751555 @default.
- W2017307812 hasConceptScore W2017307812C2776885963 @default.
- W2017307812 hasConceptScore W2017307812C55493867 @default.
- W2017307812 hasConceptScore W2017307812C71240020 @default.
- W2017307812 hasConceptScore W2017307812C71924100 @default.
- W2017307812 hasConceptScore W2017307812C98274493 @default.
- W2017307812 hasLocation W20173078121 @default.
- W2017307812 hasLocation W20173078122 @default.
- W2017307812 hasOpenAccess W2017307812 @default.
- W2017307812 hasPrimaryLocation W20173078121 @default.
- W2017307812 hasRelatedWork W1968574254 @default.
- W2017307812 hasRelatedWork W1994309439 @default.
- W2017307812 hasRelatedWork W2005773236 @default.
- W2017307812 hasRelatedWork W2011120664 @default.
- W2017307812 hasRelatedWork W2025989666 @default.
- W2017307812 hasRelatedWork W2031931692 @default.
- W2017307812 hasRelatedWork W2040885616 @default.
- W2017307812 hasRelatedWork W2048886814 @default.
- W2017307812 hasRelatedWork W2052979291 @default.
- W2017307812 hasRelatedWork W2053999634 @default.
- W2017307812 hasRelatedWork W2064544115 @default.
- W2017307812 hasRelatedWork W2078135230 @default.
- W2017307812 hasRelatedWork W2129482588 @default.
- W2017307812 hasRelatedWork W2184140451 @default.
- W2017307812 hasRelatedWork W2324504224 @default.
- W2017307812 hasRelatedWork W2403085956 @default.
- W2017307812 hasRelatedWork W2564452493 @default.
- W2017307812 hasRelatedWork W2593160826 @default.
- W2017307812 hasRelatedWork W3013455635 @default.
- W2017307812 hasRelatedWork W2867088481 @default.
- W2017307812 isParatext "false" @default.
- W2017307812 isRetracted "false" @default.
- W2017307812 magId "2017307812" @default.
- W2017307812 workType "article" @default.