FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017313377> ?p ?o ?g. }

• W2017313377 endingPage "316" @default.
• W2017313377 startingPage "297" @default.
• W2017313377 abstract "As retinoic acid (RA) is known to regulate the expression of many neuronal proteins, it is likely to influence overall development and function of the brain; few particulars, however, are available about its role in neurobiological contexts due mainly to problems in RA detection. To ask whether the function of RA in the rostral brain is concentrated in particular neurobiological systems, we compared sites of RA synthesis and actions, as detected by RA signaling in reporter mice, for embryonic and adult ages. We found that most sites of RA actions in the forebrain do not colocalize with RA synthesis, consistent with a dominant RA supply by diffusion and the circulation. The changing RA patterns distinguish preferentially two complex functional schemes. (1) Within the visual system when the first optic axons grow toward their targets, RA signaling delineates the topographical adjustment of the retinal map, which is encoded in the coordinates of the visual world, to central visual maps, which are formed in the segmental brain coordinates. (2) The second scheme begins early in forebrain morphogenesis as a distinction of the dorsal telencephalon. With progressing development, and in the adult, the RA patterns then focus on widely distributed structures, most of which belong to the limbic system. These are sites in which emotional perception is combined with higher cognitive processes and in which normal function requires ongoing remodeling of synaptic connections, indicating that the developmental role of RA in promotion of neuronal differentiation programs continues in the adult brain for highly flexible neural circuits. J. Comp. Neurol. 470:297-316, 2004." @default.
• W2017313377 created "2016-06-24" @default.
• W2017313377 creator A5040362385 @default.
• W2017313377 creator A5055464257 @default.
• W2017313377 creator A5076029463 @default.
• W2017313377 creator A5088452407 @default.
• W2017313377 date "2004-01-26" @default.
• W2017313377 modified "2023-10-17" @default.
• W2017313377 title "Retinoic acid signaling in the brain marks formation of optic projections, maturation of the dorsal telencephalon, and function of limbic sites" @default.
• W2017313377 cites W1527331090 @default.
• W2017313377 cites W1527976882 @default.
• W2017313377 cites W1841957993 @default.
• W2017313377 cites W1888417808 @default.
• W2017313377 cites W1911871301 @default.
• W2017313377 cites W1934664389 @default.
• W2017313377 cites W1936962732 @default.
• W2017313377 cites W1937034524 @default.
• W2017313377 cites W1963895870 @default.
• W2017313377 cites W1967720940 @default.
• W2017313377 cites W1968164494 @default.
• W2017313377 cites W1972530481 @default.
• W2017313377 cites W1973726394 @default.
• W2017313377 cites W1976405146 @default.
• W2017313377 cites W1980397209 @default.
• W2017313377 cites W1980451933 @default.
• W2017313377 cites W1980768299 @default.
• W2017313377 cites W1980976351 @default.
• W2017313377 cites W1981690203 @default.
• W2017313377 cites W1990789332 @default.
• W2017313377 cites W1997815735 @default.
• W2017313377 cites W2000901564 @default.
• W2017313377 cites W2003401511 @default.
• W2017313377 cites W2003928686 @default.
• W2017313377 cites W2005883936 @default.
• W2017313377 cites W2007081540 @default.
• W2017313377 cites W2011467252 @default.
• W2017313377 cites W2016146562 @default.
• W2017313377 cites W2019997163 @default.
• W2017313377 cites W2021047790 @default.
• W2017313377 cites W2022696313 @default.
• W2017313377 cites W2023003508 @default.
• W2017313377 cites W2023928947 @default.
• W2017313377 cites W2025135710 @default.
• W2017313377 cites W2028236635 @default.
• W2017313377 cites W2034927169 @default.
• W2017313377 cites W2038639188 @default.
• W2017313377 cites W2041710680 @default.
• W2017313377 cites W2042888750 @default.
• W2017313377 cites W2044596847 @default.
• W2017313377 cites W2045232172 @default.
• W2017313377 cites W2046859370 @default.
• W2017313377 cites W2047419060 @default.
• W2017313377 cites W2047673461 @default.
• W2017313377 cites W2063620761 @default.
• W2017313377 cites W2071230039 @default.
• W2017313377 cites W2074658209 @default.
• W2017313377 cites W2080898508 @default.
• W2017313377 cites W2083761568 @default.
• W2017313377 cites W2085116251 @default.
• W2017313377 cites W2091181040 @default.
• W2017313377 cites W2092488865 @default.
• W2017313377 cites W2098056422 @default.
• W2017313377 cites W2104407210 @default.
• W2017313377 cites W2109887989 @default.
• W2017313377 cites W2112672557 @default.
• W2017313377 cites W2112731799 @default.
• W2017313377 cites W2122827236 @default.
• W2017313377 cites W2125161058 @default.
• W2017313377 cites W2132094916 @default.
• W2017313377 cites W2156684099 @default.
• W2017313377 cites W2156984202 @default.
• W2017313377 cites W2159617943 @default.
• W2017313377 cites W2164648160 @default.
• W2017313377 cites W2165108884 @default.
• W2017313377 cites W2167214853 @default.
• W2017313377 cites W2172256092 @default.
• W2017313377 cites W238009640 @default.
• W2017313377 cites W4302034747 @default.
• W2017313377 doi "https://doi.org/10.1002/cne.20013" @default.
• W2017313377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14755518" @default.
• W2017313377 hasPublicationYear "2004" @default.
• W2017313377 type Work @default.
• W2017313377 sameAs 2017313377 @default.
• W2017313377 citedByCount "61" @default.
• W2017313377 countsByYear W20173133772012 @default.
• W2017313377 countsByYear W20173133772013 @default.
• W2017313377 countsByYear W20173133772014 @default.
• W2017313377 countsByYear W20173133772015 @default.
• W2017313377 countsByYear W20173133772016 @default.
• W2017313377 countsByYear W20173133772017 @default.
• W2017313377 countsByYear W20173133772019 @default.
• W2017313377 countsByYear W20173133772020 @default.
• W2017313377 countsByYear W20173133772021 @default.
• W2017313377 countsByYear W20173133772022 @default.
• W2017313377 crossrefType "journal-article" @default.
• W2017313377 hasAuthorship W2017313377A5040362385 @default.
• W2017313377 hasAuthorship W2017313377A5055464257 @default.
• W2017313377 hasAuthorship W2017313377A5076029463 @default.

• next