FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017331347> ?p ?o ?g. }

• W2017331347 endingPage "609" @default.
• W2017331347 startingPage "599" @default.
• W2017331347 abstract "Prader-Willi syndrome (PWS) is a neurobehavioral disorder that is due to the loss of multiple, paternally-expressed, imprinted genes on human chromosome 15q11-q13. The candidate genes are conserved in mice and are located in an orthologous region on mouse 7C. Several mouse models in which one or more of the PWS candidate genes are silenced do not recapitulate the full PWS phenotype. We examined the expression patterns of the mouse orthologues of PWS candidate genes throughout the development of the brain regions most implicated in PWS, including the hypothalamus, pituitary, forebrain and hindbrain. Snrpn, Ipw and Ndn are widely expressed at high levels throughout the mouse brain, whereas Magel2, Mkrn3 and the snoRNA MBII-85 are preferentially expressed in specific brain regions. Magel2 is most specifically expressed in developing hypothalamus, the region of the brain implicated in PWS hyperphagia and obesity. Although Snrpn, Ipw and MBII-85 are putatively transcribed from the same promoter, the transcripts are differentially detected in neural tissues. The analysis of expression patterns of murine orthologues of human disease genes is valuable for identifying sites of gene expression that correlate with disease phenotype." @default.
• W2017331347 created "2016-06-24" @default.
• W2017331347 creator A5018455500 @default.
• W2017331347 creator A5035254171 @default.
• W2017331347 creator A5078568633 @default.
• W2017331347 date "2003-10-01" @default.
• W2017331347 modified "2023-10-15" @default.
• W2017331347 title "Prader–Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain" @default.
• W2017331347 cites W1502309883 @default.
• W2017331347 cites W1542932778 @default.
• W2017331347 cites W1831769215 @default.
• W2017331347 cites W1871197503 @default.
• W2017331347 cites W1964340841 @default.
• W2017331347 cites W1972618461 @default.
• W2017331347 cites W1976403210 @default.
• W2017331347 cites W1976543350 @default.
• W2017331347 cites W1977047462 @default.
• W2017331347 cites W1979216378 @default.
• W2017331347 cites W1988296630 @default.
• W2017331347 cites W1989755873 @default.
• W2017331347 cites W1991021245 @default.
• W2017331347 cites W1992218856 @default.
• W2017331347 cites W1999203392 @default.
• W2017331347 cites W2002803683 @default.
• W2017331347 cites W2003849576 @default.
• W2017331347 cites W2010841319 @default.
• W2017331347 cites W2013353304 @default.
• W2017331347 cites W2016192465 @default.
• W2017331347 cites W2020949876 @default.
• W2017331347 cites W2021629503 @default.
• W2017331347 cites W2022372415 @default.
• W2017331347 cites W2022756254 @default.
• W2017331347 cites W2025310562 @default.
• W2017331347 cites W2029117845 @default.
• W2017331347 cites W2034921729 @default.
• W2017331347 cites W2036708294 @default.
• W2017331347 cites W2036805817 @default.
• W2017331347 cites W2039055915 @default.
• W2017331347 cites W2039499622 @default.
• W2017331347 cites W2041056467 @default.
• W2017331347 cites W2042289885 @default.
• W2017331347 cites W2045857484 @default.
• W2017331347 cites W2046382497 @default.
• W2017331347 cites W2047537443 @default.
• W2017331347 cites W2049556237 @default.
• W2017331347 cites W2052142601 @default.
• W2017331347 cites W2053022831 @default.
• W2017331347 cites W2057625382 @default.
• W2017331347 cites W2060187824 @default.
• W2017331347 cites W2061639735 @default.
• W2017331347 cites W2068134092 @default.
• W2017331347 cites W2069169829 @default.
• W2017331347 cites W2069290560 @default.
• W2017331347 cites W2070766068 @default.
• W2017331347 cites W2077235717 @default.
• W2017331347 cites W2078944460 @default.
• W2017331347 cites W2081530732 @default.
• W2017331347 cites W2087897472 @default.
• W2017331347 cites W2093760946 @default.
• W2017331347 cites W2099392167 @default.
• W2017331347 cites W2101600063 @default.
• W2017331347 cites W2106874662 @default.
• W2017331347 cites W2119853384 @default.
• W2017331347 cites W2121774805 @default.
• W2017331347 cites W2128765086 @default.
• W2017331347 cites W2134548352 @default.
• W2017331347 cites W2141942950 @default.
• W2017331347 cites W2144413095 @default.
• W2017331347 cites W2145843666 @default.
• W2017331347 cites W2146105594 @default.
• W2017331347 cites W2147714004 @default.
• W2017331347 cites W2147977861 @default.
• W2017331347 cites W2148641958 @default.
• W2017331347 cites W2149070866 @default.
• W2017331347 cites W2153415070 @default.
• W2017331347 cites W2155060440 @default.
• W2017331347 cites W2156199849 @default.
• W2017331347 cites W2161565570 @default.
• W2017331347 cites W2161688901 @default.
• W2017331347 cites W2164901992 @default.
• W2017331347 cites W2168068215 @default.
• W2017331347 cites W2169243271 @default.
• W2017331347 cites W2414959281 @default.
• W2017331347 cites W2496258569 @default.
• W2017331347 cites W2887188667 @default.
• W2017331347 cites W608227570 @default.
• W2017331347 cites W81221420 @default.
• W2017331347 cites W2076002758 @default.
• W2017331347 doi "https://doi.org/10.1016/s1567-133x(03)00113-3" @default.
• W2017331347 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12971993" @default.
• W2017331347 hasPublicationYear "2003" @default.
• W2017331347 type Work @default.
• W2017331347 sameAs 2017331347 @default.
• W2017331347 citedByCount "74" @default.
• W2017331347 countsByYear W20173313472012 @default.
• W2017331347 countsByYear W20173313472013 @default.
• W2017331347 countsByYear W20173313472014 @default.
• W2017331347 countsByYear W20173313472015 @default.

• next