FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017334411> ?p ?o ?g. }

• W2017334411 endingPage "20" @default.
• W2017334411 startingPage "14" @default.
• W2017334411 abstract "Background Ghrelin is a growth hormone secretagogue. It is a potent regulator of energy homeostasis. Ghrelin concentration is down‐regulated in humans with hypersomatotropism ( HS ) and increases after successful treatment. Additionally, ghrelin secretion seems impaired in human diabetes mellitus ( DM ). Hypothesis Serum ghrelin concentration is down‐regulated in cats with HS ‐induced DM ( HSDM ) compared to healthy control cats or cats with DM unrelated to HS and increases after radiotherapy. Animals Cats with DM (n = 20) and with HSDM (n = 32), 13 of which underwent radiotherapy ( RT ‐group); age‐matched controls (n = 20). Methods Retrospective cross‐sectional study. Analytical performance of a serum total ghrelin ELISA was assessed and validated for use in cats. Differences in serum ghrelin, fructosamine, IGF ‐1 and insulin were evaluated. Results Ghrelin was significantly higher ( P < .001) in control cats (mean ± SD: 12.9 ± 6.8 ng/mL) compared to HSDM ‐ (7.9 ± 3.3 ng/mL) and DM ‐cats (6.7 ± 2.3 ng/mL), although not different between the HSDM ‐ and DM ‐cats. After RT ghrelin increased significantly ( P = .003) in HSDM ‐cats undergoing RT (from 6.6 ± 1.9 ng/mL to 9.0 ± 2.2 ng/mL) and the after RT ghrelin concentrations of HSDM cats were no longer significantly different from the serum ghrelin concentration of control cats. Serum IGF ‐1 did not significantly change in HSDM ‐cats after RT , despite significant decreases in fructosamine and insulin dose. Conclusion and Clinical Importance Ghrelin appears suppressed in cats with DM and HSDM , although increases after RT in HSDM , suggesting possible presence of a direct or indirect negative feedback system between growth hormone and ghrelin. Serum ghrelin might therefore represent a marker of treatment effect." @default.
• W2017334411 created "2016-06-24" @default.
• W2017334411 creator A5030434721 @default.
• W2017334411 creator A5072590685 @default.
• W2017334411 creator A5081002218 @default.
• W2017334411 creator A5091136519 @default.
• W2017334411 date "2015-01-01" @default.
• W2017334411 modified "2023-10-12" @default.
• W2017334411 title "Evaluation and Diagnostic Potential of Serum Ghrelin in Feline Hypersomatotropism and Diabetes Mellitus" @default.
• W2017334411 cites W1964069521 @default.
• W2017334411 cites W1972927790 @default.
• W2017334411 cites W1979748274 @default.
• W2017334411 cites W1980664585 @default.
• W2017334411 cites W1985114282 @default.
• W2017334411 cites W1985643446 @default.
• W2017334411 cites W1987944386 @default.
• W2017334411 cites W1988062726 @default.
• W2017334411 cites W1996286776 @default.
• W2017334411 cites W1998289958 @default.
• W2017334411 cites W2001044066 @default.
• W2017334411 cites W2004406564 @default.
• W2017334411 cites W2006388337 @default.
• W2017334411 cites W2013072242 @default.
• W2017334411 cites W2014252560 @default.
• W2017334411 cites W2025196522 @default.
• W2017334411 cites W2026168793 @default.
• W2017334411 cites W2032225465 @default.
• W2017334411 cites W2053277956 @default.
• W2017334411 cites W2065093334 @default.
• W2017334411 cites W2071196137 @default.
• W2017334411 cites W2071265085 @default.
• W2017334411 cites W2073055216 @default.
• W2017334411 cites W2075571229 @default.
• W2017334411 cites W2099431125 @default.
• W2017334411 cites W2110238271 @default.
• W2017334411 cites W2112202133 @default.
• W2017334411 cites W2113628166 @default.
• W2017334411 cites W2114295425 @default.
• W2017334411 cites W2119580431 @default.
• W2017334411 cites W2123204053 @default.
• W2017334411 cites W2125929781 @default.
• W2017334411 cites W2132676982 @default.
• W2017334411 cites W2138707307 @default.
• W2017334411 cites W2139789471 @default.
• W2017334411 cites W2147507987 @default.
• W2017334411 cites W2154432452 @default.
• W2017334411 cites W2155946960 @default.
• W2017334411 cites W2162446642 @default.
• W2017334411 cites W2163865122 @default.
• W2017334411 cites W2166209517 @default.
• W2017334411 cites W4236140022 @default.
• W2017334411 cites W4241558923 @default.
• W2017334411 doi "https://doi.org/10.1111/jvim.12536" @default.
• W2017334411 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4858111" @default.
• W2017334411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25619512" @default.
• W2017334411 hasPublicationYear "2015" @default.
• W2017334411 type Work @default.
• W2017334411 sameAs 2017334411 @default.
• W2017334411 citedByCount "8" @default.
• W2017334411 countsByYear W20173344112016 @default.
• W2017334411 countsByYear W20173344112017 @default.
• W2017334411 countsByYear W20173344112018 @default.
• W2017334411 countsByYear W20173344112021 @default.
• W2017334411 countsByYear W20173344112022 @default.
• W2017334411 countsByYear W20173344112023 @default.
• W2017334411 crossrefType "journal-article" @default.
• W2017334411 hasAuthorship W2017334411A5030434721 @default.
• W2017334411 hasAuthorship W2017334411A5072590685 @default.
• W2017334411 hasAuthorship W2017334411A5081002218 @default.
• W2017334411 hasAuthorship W2017334411A5091136519 @default.
• W2017334411 hasBestOaLocation W20173344112 @default.
• W2017334411 hasConcept C126322002 @default.
• W2017334411 hasConcept C134018914 @default.
• W2017334411 hasConcept C2779357093 @default.
• W2017334411 hasConcept C2779904517 @default.
• W2017334411 hasConcept C2781357877 @default.
• W2017334411 hasConcept C555293320 @default.
• W2017334411 hasConcept C71315377 @default.
• W2017334411 hasConcept C71924100 @default.
• W2017334411 hasConceptScore W2017334411C126322002 @default.
• W2017334411 hasConceptScore W2017334411C134018914 @default.
• W2017334411 hasConceptScore W2017334411C2779357093 @default.
• W2017334411 hasConceptScore W2017334411C2779904517 @default.
• W2017334411 hasConceptScore W2017334411C2781357877 @default.
• W2017334411 hasConceptScore W2017334411C555293320 @default.
• W2017334411 hasConceptScore W2017334411C71315377 @default.
• W2017334411 hasConceptScore W2017334411C71924100 @default.
• W2017334411 hasIssue "1" @default.
• W2017334411 hasLocation W20173344111 @default.
• W2017334411 hasLocation W20173344112 @default.
• W2017334411 hasLocation W20173344113 @default.
• W2017334411 hasLocation W20173344114 @default.
• W2017334411 hasOpenAccess W2017334411 @default.
• W2017334411 hasPrimaryLocation W20173344111 @default.
• W2017334411 hasRelatedWork W2003577251 @default.
• W2017334411 hasRelatedWork W2029765733 @default.
• W2017334411 hasRelatedWork W2048194663 @default.
• W2017334411 hasRelatedWork W2093337002 @default.

• next