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- W2017335503 abstract "The glycoprotein hormones luteinizing hormone (LH) and chorionic gonadotrophin (CG) are crucial for reproduction, as LH induces sex hormone production and ovulation, and CG is essential for the establishment of pregnancy and fetal male sexual differentiation. Both consist of two heterodimeric peptides of which the α-subunit is common to both hormones whereas the β-subunit is hormone-specific. The CGB gene was derived from LHB by gene duplication and frame shift mutation that led to a read-through into the formerly 3′-untranslated region, giving rise to the carboxyl-terminal peptide. Owing to nucleotide changes within the 5′-region of CGB, a new transcriptional start site and regulatory region was gained. These changes led to the specific expression of CGB in the placenta and its decrease in the pituitary. Recent findings on gonadotrophins led to an extended model for the sequence of events in the evolution of the CGB gene in primates and its tissue-specific expression." @default.
- W2017335503 created "2016-06-24" @default.
- W2017335503 creator A5048402117 @default.
- W2017335503 creator A5053394505 @default.
- W2017335503 date "2008-09-01" @default.
- W2017335503 modified "2023-10-18" @default.
- W2017335503 title "New insights into the evolution of chorionic gonadotrophin" @default.
- W2017335503 cites W1037454573 @default.
- W2017335503 cites W1487072100 @default.
- W2017335503 cites W1510604115 @default.
- W2017335503 cites W1517707427 @default.
- W2017335503 cites W1552057761 @default.
- W2017335503 cites W1580198172 @default.
- W2017335503 cites W1584201864 @default.
- W2017335503 cites W1594381616 @default.
- W2017335503 cites W1689369637 @default.
- W2017335503 cites W1860835363 @default.
- W2017335503 cites W1969918461 @default.
- W2017335503 cites W1970800566 @default.
- W2017335503 cites W1971231926 @default.
- W2017335503 cites W1974959443 @default.
- W2017335503 cites W1979087671 @default.
- W2017335503 cites W1979093625 @default.
- W2017335503 cites W1981636788 @default.
- W2017335503 cites W1986617857 @default.
- W2017335503 cites W1988008131 @default.
- W2017335503 cites W1989474303 @default.
- W2017335503 cites W1990894916 @default.
- W2017335503 cites W1991983658 @default.
- W2017335503 cites W1992174768 @default.
- W2017335503 cites W1992899654 @default.
- W2017335503 cites W1993178390 @default.
- W2017335503 cites W1997260729 @default.
- W2017335503 cites W1998937141 @default.
- W2017335503 cites W2000522767 @default.
- W2017335503 cites W2002077649 @default.
- W2017335503 cites W2004470989 @default.
- W2017335503 cites W2006192389 @default.
- W2017335503 cites W2006673026 @default.
- W2017335503 cites W2008350862 @default.
- W2017335503 cites W2010677182 @default.
- W2017335503 cites W2011493779 @default.
- W2017335503 cites W2014688379 @default.
- W2017335503 cites W2015427249 @default.
- W2017335503 cites W2017121407 @default.
- W2017335503 cites W2017951498 @default.
- W2017335503 cites W2019251281 @default.
- W2017335503 cites W2027660118 @default.
- W2017335503 cites W2028612664 @default.
- W2017335503 cites W2029669342 @default.
- W2017335503 cites W2031192188 @default.
- W2017335503 cites W2032652080 @default.
- W2017335503 cites W2034807717 @default.
- W2017335503 cites W2035642037 @default.
- W2017335503 cites W2038016430 @default.
- W2017335503 cites W2038465053 @default.
- W2017335503 cites W2042671665 @default.
- W2017335503 cites W2042898424 @default.
- W2017335503 cites W2044359552 @default.
- W2017335503 cites W2046646544 @default.
- W2017335503 cites W2050838935 @default.
- W2017335503 cites W2050971119 @default.
- W2017335503 cites W2051416501 @default.
- W2017335503 cites W2053380617 @default.
- W2017335503 cites W2053578325 @default.
- W2017335503 cites W2054617410 @default.
- W2017335503 cites W2069370276 @default.
- W2017335503 cites W2069814833 @default.
- W2017335503 cites W2072015758 @default.
- W2017335503 cites W2077016255 @default.
- W2017335503 cites W2077546371 @default.
- W2017335503 cites W2078121284 @default.
- W2017335503 cites W2079809058 @default.
- W2017335503 cites W2081247796 @default.
- W2017335503 cites W2084502179 @default.
- W2017335503 cites W2085562009 @default.
- W2017335503 cites W2089662710 @default.
- W2017335503 cites W2090465502 @default.
- W2017335503 cites W2090853355 @default.
- W2017335503 cites W2092117743 @default.
- W2017335503 cites W2094621094 @default.
- W2017335503 cites W2100496553 @default.
- W2017335503 cites W2101496780 @default.
- W2017335503 cites W2104618341 @default.
- W2017335503 cites W2107393031 @default.
- W2017335503 cites W2109006736 @default.
- W2017335503 cites W2109473825 @default.
- W2017335503 cites W2111999181 @default.
- W2017335503 cites W2113313069 @default.
- W2017335503 cites W2116048028 @default.
- W2017335503 cites W2122371619 @default.
- W2017335503 cites W2123396334 @default.
- W2017335503 cites W2125548284 @default.
- W2017335503 cites W2129788378 @default.
- W2017335503 cites W2134367837 @default.
- W2017335503 cites W2134714685 @default.
- W2017335503 cites W2137594228 @default.
- W2017335503 cites W2139643583 @default.