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• W2017338994 abstract "Death-associated protein kinases (DAPKs) function in the early stages of eukaryotic programmed cell death. DAPKs are now emerging as targets for drug discovery in novel therapeutic approaches for ischemic diseases in the brain, heart, kidney, and other organs. Using a structure-based virtual screening approach, we discovered potent and selective DAPKs inhibitors. 6 was found to be the most potent inhibitor with enzyme selectivity (IC(50) = 69 nM for DAPK1)." @default.
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• W2017338994 date "2009-10-30" @default.
• W2017338994 modified "2023-10-14" @default.
• W2017338994 title "Identification of Death-Associated Protein Kinases Inhibitors Using Structure-Based Virtual Screening" @default.
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• W2017338994 doi "https://doi.org/10.1021/jm901191q" @default.
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