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• W2017339994 abstract "After thyroidectomy hypocalcaemia is the most significant complication for clinicians. In this study, we investigated the factors associated with development of hypocalcaemia after thyroidectomy.We investigated the patients prospectively for age, gender, preoperative diagnosis, hormonal status, operative time, operating surgeon, existence of parathyroid gland injury at the operation, parathyroid gland auto-transplantation, preoperative use of anti-thyroid drugs and amount of bleeding at the operation. After operation in 1 and 2 days, serum calcium and phosphor, and in the 1 day parathyroid hormone values were evaluated. The chi-square test was applied in the analysis of categorical variables. Logistic regression model was used to determine the risk of hypocalcaemia in the univariate analysis.Hypocalcaemia developed in 47 of 196 patients. Female gender, preoperative diagnosis of thyroid cancer and toxic nodular goitre, <3cm nodule size, parathyroid injury and auto-transplantation and low vitamin D levels were factors found to be associated with hypocalcaemia in the Logistic regression analysis.The factors associated with hypocalcaemia were defined to be gender, preoperative diagnosis, parathyroid gland injury, nodule size and vitamin D deficiency, it is a multifactorial problem and it would not be proper to define a few etiological factors.Tiroidektomi sonrası hipokalsemi tiroid ameliyatlarının en sık karşılaşılan komplikasyonlarından olup günümüzde klinisyenler açısından hala önemini korumaktadır. Biz bu çalışmada tiroidektomi sonrası hipokalsemi gelişmesine etki eden faktörleri araştırdık.Hastaların prospektif olarak yaş, cinsiyet, preoperatif tanı, hormonal durum, ameliyat süresi, ameliyatı yapan doktor, ameliyatta paratiroid hasarı olup olmadığı, paratiroid ototransplantasyonu yapılıp yapılmadığı, ameliyat oncesi antitiroid ajan kullanıp kullanmadığı, ameliyattaki kanama miktarları yönünden değerlendirildi. Ameliyattan sonra 1. ve 2. günlerde serum kalsiyum ve fosfor, 1. günde paratiroid hormon düzeylerine bakıldı.. Kategorik değişkenlerde ki-kare testi uygulandı. Tek değişkenli analizlerde hipokalsemi riskini belirlemek için lojistik regresyon modeli uygulandı.Hastaların 47’sinde hipokalsemi bulguları geliştiği görüldü. Hipokalsemi bulguları gelişen hastalarda, cinsiyetin kadın olmasının, preoperatif tanının tiroid kanseri ve toksik noduler guatr olmasının, nodül boyutunun 3 cm’den küçük olmasının, paratiroid hasarı ve ototransplantasyon yapılmış olmasının, vitamin D düzeyinin düşük olmasının hipokalsemi gelişmesi ile ilişkili olduğu görüldü.Çalışmamızda hipokalsemi bulguları gelişmesi üzerine etkili faktörler “cinsiyet, preoperatif tanı, paratiroid hasarı, nodül boyutları ve Vitamin D eksikliği” olarak bulunmasına rağmen, hipokalsemi etyolojinin sadece bu faktörlere bağlamak doğru olmaz, bu daha çok multifaktoriyel bir durumdur." @default.
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• W2017339994 date "2014-02-27" @default.
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• W2017339994 title "Factors Affecting Hypocalcaemia Following Total Thyroidectomy: A Prospective Study" @default.
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• W2017339994 doi "https://doi.org/10.5152/eajm.2014.03" @default.
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