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- W2017341645 abstract "Isolated whole canine stomachs, perfused ex vivo with homologous blood, were used for studying the effect of 16,16-dimethyl prostaglandin-E2 (dmPGE2) on gastric secretion. DmPGE2 was administered either into the gastric artery or instilled intragastrically through an esophageal cannula. Histamine, infused intra-arterially, induced acid secretion of all ex vivo stomachs and this was significantly inhibited by intra-arterially or intra-gastrically administered dmPGE2: volume of secretion, output of HCl and concentration of H+ were decreased and gastric peripheral vascular resistance was significantly reduced. The inhibitory action of dmPGE2 continued after its administration was stopped." @default.
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- W2017341645 date "1978-05-01" @default.
- W2017341645 modified "2023-09-23" @default.
- W2017341645 title "Effect of 16,16-dimethyl prostaglandin-E2 given intra-arterially or intra-gastrically, on acid secretion by canine stomachs perfused ex vivo" @default.
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- W2017341645 doi "https://doi.org/10.1016/0090-6980(78)90157-0" @default.
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