Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017343387> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2017343387 abstract "Pentaploid H1 (ES) cells (5H1 cells) were accidentally obtained through one-cell cloning of octaploid H1 (ES) cells (8H1 cells) that were established from tetraploid H1 (ES) cells (4H1 cells) polyploidized using demecolcine. The number of chromosomes of 5H1 cells was 100, unlike the 40 of diploid H1 (ES) cells (2H1 cells), 80 of 4H1, and 160 of 8H1 cells. The durations of G(1), S, and G(2)/M phases of 5H1 cells were 3, 7, and 6 h, respectively, almost the same as those of 2H1, 4H1, and 8H1 cells. The cell volume of 5H1 cells was half of that of 8H1 cells, suggesting that 5H1 cells were created through abnormal cell divisions of 8H1 cells. The morphology of growing 5H1 cells was a spherical cluster similar to that of 2H1 cells and differing from the flagstone-like shape of 4H1 and 8H1 cells. Pentaploid solid tumors were formed from 5H1 cells after interperitoneal injection into the mouse abdomen, and they contained endodermal, mesodermal, and ectodermal cells as well as undifferentiated cells, suggesting both that the DNA content of 5H1 cells was retained during tumor formation and that the 5H1 cells were pluripotent. The DNA content of 5H1 cells was stable in long-term culturing as 2H1 cells, meaning that 5H1 and 2H1 cells shared similarities in DNA structure. The excellent stability of the DNA content of 5H1 cells was explained using a hypothesis for the DNA structure of polyploid cells because the pairing of homologous chromosomes in 5H1 cells is spatially forbidden." @default.
- W2017343387 created "2016-06-24" @default.
- W2017343387 creator A5007728080 @default.
- W2017343387 creator A5025991728 @default.
- W2017343387 creator A5039185693 @default.
- W2017343387 creator A5039833530 @default.
- W2017343387 date "2010-01-01" @default.
- W2017343387 modified "2023-09-26" @default.
- W2017343387 title "DNA stable pentaploid H1 (ES) cells obtained from an octaploid cell induced from tetraploid cells polyploidized using demecolcine" @default.
- W2017343387 cites W1566167018 @default.
- W2017343387 cites W1967532516 @default.
- W2017343387 cites W1992519294 @default.
- W2017343387 cites W2000692784 @default.
- W2017343387 cites W2001382398 @default.
- W2017343387 cites W2005175547 @default.
- W2017343387 cites W2007810274 @default.
- W2017343387 cites W2039742703 @default.
- W2017343387 cites W2040878969 @default.
- W2017343387 cites W2041020465 @default.
- W2017343387 cites W2041978368 @default.
- W2017343387 cites W2042323878 @default.
- W2017343387 cites W2042976490 @default.
- W2017343387 cites W2049342100 @default.
- W2017343387 cites W2050254783 @default.
- W2017343387 cites W2059886017 @default.
- W2017343387 cites W2062656476 @default.
- W2017343387 cites W2069872659 @default.
- W2017343387 cites W2072638636 @default.
- W2017343387 cites W2078558757 @default.
- W2017343387 cites W2095358445 @default.
- W2017343387 cites W2164421534 @default.
- W2017343387 cites W2169790726 @default.
- W2017343387 cites W2330028882 @default.
- W2017343387 doi "https://doi.org/10.1002/jcp.22042" @default.
- W2017343387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20082301" @default.
- W2017343387 hasPublicationYear "2010" @default.
- W2017343387 type Work @default.
- W2017343387 sameAs 2017343387 @default.
- W2017343387 citedByCount "0" @default.
- W2017343387 crossrefType "journal-article" @default.
- W2017343387 hasAuthorship W2017343387A5007728080 @default.
- W2017343387 hasAuthorship W2017343387A5025991728 @default.
- W2017343387 hasAuthorship W2017343387A5039185693 @default.
- W2017343387 hasAuthorship W2017343387A5039833530 @default.
- W2017343387 hasConcept C104317684 @default.
- W2017343387 hasConcept C143191323 @default.
- W2017343387 hasConcept C1491633281 @default.
- W2017343387 hasConcept C153911025 @default.
- W2017343387 hasConcept C54355233 @default.
- W2017343387 hasConcept C552990157 @default.
- W2017343387 hasConcept C86803240 @default.
- W2017343387 hasConcept C95444343 @default.
- W2017343387 hasConceptScore W2017343387C104317684 @default.
- W2017343387 hasConceptScore W2017343387C143191323 @default.
- W2017343387 hasConceptScore W2017343387C1491633281 @default.
- W2017343387 hasConceptScore W2017343387C153911025 @default.
- W2017343387 hasConceptScore W2017343387C54355233 @default.
- W2017343387 hasConceptScore W2017343387C552990157 @default.
- W2017343387 hasConceptScore W2017343387C86803240 @default.
- W2017343387 hasConceptScore W2017343387C95444343 @default.
- W2017343387 hasLocation W20173433871 @default.
- W2017343387 hasLocation W20173433872 @default.
- W2017343387 hasOpenAccess W2017343387 @default.
- W2017343387 hasPrimaryLocation W20173433871 @default.
- W2017343387 hasRelatedWork W1479963757 @default.
- W2017343387 hasRelatedWork W1507479692 @default.
- W2017343387 hasRelatedWork W1554399117 @default.
- W2017343387 hasRelatedWork W1967532516 @default.
- W2017343387 hasRelatedWork W1992519294 @default.
- W2017343387 hasRelatedWork W2040878969 @default.
- W2017343387 hasRelatedWork W2042323878 @default.
- W2017343387 hasRelatedWork W2043937467 @default.
- W2017343387 hasRelatedWork W2050254783 @default.
- W2017343387 hasRelatedWork W2054211223 @default.
- W2017343387 hasRelatedWork W2062656476 @default.
- W2017343387 hasRelatedWork W2072638636 @default.
- W2017343387 hasRelatedWork W2078558757 @default.
- W2017343387 hasRelatedWork W2086165050 @default.
- W2017343387 hasRelatedWork W2095358445 @default.
- W2017343387 hasRelatedWork W2164421534 @default.
- W2017343387 hasRelatedWork W2169790726 @default.
- W2017343387 hasRelatedWork W2330028882 @default.
- W2017343387 hasRelatedWork W2427593458 @default.
- W2017343387 hasRelatedWork W2472745371 @default.
- W2017343387 isParatext "false" @default.
- W2017343387 isRetracted "false" @default.
- W2017343387 magId "2017343387" @default.
- W2017343387 workType "article" @default.