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• W2017347239 abstract "The essential role of platelets in haemostasis underlies the relationship between platelet function and spontaneous or procedure-related bleeding, which has important prognostic implications. Although not routinely undertaken, platelet function testing offers the potential to tailor antiplatelet therapy for individual patients. However, uncertainties remain about how well platelet function testing may predict haemostasis and guide management of bleeding risk. Studies of aspirin, P2Y12 inhibitors and other antiplatelet drugs clearly demonstrate how inhibition of platelet function increases bleeding risk. More potent antiplatelet drugs are associated with higher bleeding rates, consistent with the levels of platelet inhibition achieved by these drugs. Studies of patients treated with clopidogrel, which is associated with wide inter-individual variation in antiplatelet effect, suggest that platelet function testing may predict bleeding risk related to coronary artery bypass grafting (CABG) surgery and potentially guide the timing of surgery following discontinuation of clopidogrel. Similarly, some studies have demonstrated a relationship between clopidogrel response and bleeding in patients undergoing percutaneous coronary intervention (PCI), although other studies have not supported this. Carriage of the *17 allele of cytochrome P450 2C19, which is associated with gain of function and enhanced response to clopidogrel, seems to be associated with increased bleeding risk, although studies showing lack of apparent effect of loss-of-function alleles provide contradictory evidence. Further large studies are needed to guide best practice in the application of platelet function testing in the clinical management of patients treated with antiplatelet drugs in order to optimise individual care." @default.
• W2017347239 created "2016-06-24" @default.
• W2017347239 creator A5011580027 @default.
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• W2017347239 date "2013-01-01" @default.
• W2017347239 modified "2023-09-25" @default.
• W2017347239 title "Platelet function testing and prediction of procedural bleeding risk" @default.
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• W2017347239 cites W1498243413 @default.
• W2017347239 cites W1503020567 @default.
• W2017347239 cites W1553345686 @default.
• W2017347239 cites W175512219 @default.
• W2017347239 cites W1965553602 @default.
• W2017347239 cites W1984537125 @default.
• W2017347239 cites W1987143431 @default.
• W2017347239 cites W1988121084 @default.
• W2017347239 cites W1998869090 @default.
• W2017347239 cites W2008000663 @default.
• W2017347239 cites W2009461799 @default.
• W2017347239 cites W2011727088 @default.
• W2017347239 cites W2011861566 @default.
• W2017347239 cites W2013560303 @default.
• W2017347239 cites W2015175766 @default.
• W2017347239 cites W2017294431 @default.
• W2017347239 cites W2020759112 @default.
• W2017347239 cites W2044070278 @default.
• W2017347239 cites W2044660277 @default.
• W2017347239 cites W2052733749 @default.
• W2017347239 cites W2053288424 @default.
• W2017347239 cites W2056489784 @default.
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• W2017347239 cites W2086708530 @default.
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• W2017347239 doi "https://doi.org/10.1160/th12-11-0806" @default.
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