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- W2017349153 abstract "Superantigens interact with major histocompatibility complex (MHC) class II molecules and T-cell receptors (TcRs) forming a trimolecular complex which is able to induce proliferation and cytokine production in T cells. Although superantigens appear to act through a common mechanism, they vary in many of their specific interactions and biological properties. X-ray crystallographic studies and biochemical experiments have now established that cross-linking of MHC class II molecules and the TcR by superantigens can occur in a number of different modes." @default.
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- W2017349153 date "1997-08-01" @default.
- W2017349153 modified "2023-10-02" @default.
- W2017349153 title "Superantigens as immunomodulators: recent structural insights" @default.
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- W2017349153 doi "https://doi.org/10.1016/s0969-2126(97)00252-9" @default.
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