Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017349212> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2017349212 abstract "Chloramphenicol is one of a number of antibiotics which specifically inhibit mitochondrial protein synthesis in eukaryotic cells, while not affecting the cytoplasmic system [ 1,2]. Some mutations conferring resistance to chloramphenicol could directly affect the mitochondrial protein synthesizing system. Studies of respiratory-deficient mutants of yeast and of Neurospora have shown that mitochondrial proteins are products of both cytoplasmic extrachromosomal determinants and of chromosomal genes [3]. The Neuro spora poky mutation, which affects mitochondrial ribosomes, exhibits nonMendelian inheritance [4]. The existence of erythromycin-, mikamycin-, and chloramphenicol-resistant yeast mutants which likewise show cytoplasmic inheritance [5-S] suggest that, in mammalian cells also, resistance to chloramphenicol may be mitochondrially coded. Extrachromosomally inherited mitochondrial mutations in mammalian cells are essential to determine gene locations of mitochondrial proteins and to study nuclear-mitochondrial interactions in mitochondrial biogenesis. This paper describes the isolation and general properties of mutants of human HeLa cells resistant to chloramphenicol." @default.
- W2017349212 created "2016-06-24" @default.
- W2017349212 creator A5035389733 @default.
- W2017349212 creator A5071543614 @default.
- W2017349212 date "1972-09-15" @default.
- W2017349212 modified "2023-09-23" @default.
- W2017349212 title "Chloramphenicol-resistant mutants of human HeLa cells" @default.
- W2017349212 cites W1506043065 @default.
- W2017349212 cites W1581118804 @default.
- W2017349212 cites W1907775921 @default.
- W2017349212 cites W1983798063 @default.
- W2017349212 cites W2021504472 @default.
- W2017349212 cites W2053654911 @default.
- W2017349212 cites W2055014375 @default.
- W2017349212 cites W2069980042 @default.
- W2017349212 cites W2076174072 @default.
- W2017349212 cites W2080696192 @default.
- W2017349212 cites W2082387146 @default.
- W2017349212 cites W2090481038 @default.
- W2017349212 cites W2103212902 @default.
- W2017349212 cites W2143211945 @default.
- W2017349212 doi "https://doi.org/10.1016/0014-5793(72)80514-3" @default.
- W2017349212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11946780" @default.
- W2017349212 hasPublicationYear "1972" @default.
- W2017349212 type Work @default.
- W2017349212 sameAs 2017349212 @default.
- W2017349212 citedByCount "78" @default.
- W2017349212 countsByYear W20173492122012 @default.
- W2017349212 crossrefType "journal-article" @default.
- W2017349212 hasAuthorship W2017349212A5035389733 @default.
- W2017349212 hasAuthorship W2017349212A5071543614 @default.
- W2017349212 hasConcept C104317684 @default.
- W2017349212 hasConcept C143065580 @default.
- W2017349212 hasConcept C153911025 @default.
- W2017349212 hasConcept C22744801 @default.
- W2017349212 hasConcept C24586158 @default.
- W2017349212 hasConcept C2778473333 @default.
- W2017349212 hasConcept C28859421 @default.
- W2017349212 hasConcept C501593827 @default.
- W2017349212 hasConcept C501734568 @default.
- W2017349212 hasConcept C54355233 @default.
- W2017349212 hasConcept C86803240 @default.
- W2017349212 hasConcept C89684784 @default.
- W2017349212 hasConcept C95444343 @default.
- W2017349212 hasConceptScore W2017349212C104317684 @default.
- W2017349212 hasConceptScore W2017349212C143065580 @default.
- W2017349212 hasConceptScore W2017349212C153911025 @default.
- W2017349212 hasConceptScore W2017349212C22744801 @default.
- W2017349212 hasConceptScore W2017349212C24586158 @default.
- W2017349212 hasConceptScore W2017349212C2778473333 @default.
- W2017349212 hasConceptScore W2017349212C28859421 @default.
- W2017349212 hasConceptScore W2017349212C501593827 @default.
- W2017349212 hasConceptScore W2017349212C501734568 @default.
- W2017349212 hasConceptScore W2017349212C54355233 @default.
- W2017349212 hasConceptScore W2017349212C86803240 @default.
- W2017349212 hasConceptScore W2017349212C89684784 @default.
- W2017349212 hasConceptScore W2017349212C95444343 @default.
- W2017349212 hasLocation W20173492121 @default.
- W2017349212 hasLocation W20173492122 @default.
- W2017349212 hasOpenAccess W2017349212 @default.
- W2017349212 hasPrimaryLocation W20173492121 @default.
- W2017349212 hasRelatedWork W14978286 @default.
- W2017349212 hasRelatedWork W1573889570 @default.
- W2017349212 hasRelatedWork W1775749144 @default.
- W2017349212 hasRelatedWork W1963614882 @default.
- W2017349212 hasRelatedWork W1979396362 @default.
- W2017349212 hasRelatedWork W1981831202 @default.
- W2017349212 hasRelatedWork W2008868445 @default.
- W2017349212 hasRelatedWork W2032254709 @default.
- W2017349212 hasRelatedWork W2038884530 @default.
- W2017349212 hasRelatedWork W2039729291 @default.
- W2017349212 hasRelatedWork W2044133901 @default.
- W2017349212 hasRelatedWork W2054757113 @default.
- W2017349212 hasRelatedWork W2057568582 @default.
- W2017349212 hasRelatedWork W2060162133 @default.
- W2017349212 hasRelatedWork W2061867442 @default.
- W2017349212 hasRelatedWork W2063390753 @default.
- W2017349212 hasRelatedWork W2071878964 @default.
- W2017349212 hasRelatedWork W2087737282 @default.
- W2017349212 hasRelatedWork W2116947837 @default.
- W2017349212 hasRelatedWork W2123990423 @default.
- W2017349212 isParatext "false" @default.
- W2017349212 isRetracted "false" @default.
- W2017349212 magId "2017349212" @default.
- W2017349212 workType "article" @default.