FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017349714> ?p ?o ?g. }

• W2017349714 endingPage "323" @default.
• W2017349714 startingPage "313" @default.
• W2017349714 abstract "CO 2 fixation is thought to be one of the key factors in mitigating global warming. Of the various methods for removing CO 2 , the NAD-dependent formate dehydrogenase from Candida boidinii (CbFDH) has been widely used in various biological CO 2 -reduction systems; however, practical applications of CbFDH have often been impeded owing to its low CO 2 -reducing activity. It has recently been demonstrated that the NAD-dependent formate dehydrogenase from Thiobacillus sp. KNK65MA (TsFDH) has a higher CO 2 -reducing activity compared with CbFDH. The crystal structure of TsFDH revealed that the biological unit in the asymmetric unit has two conformations, i.e. open (NAD + -unbound) and closed (NAD + -bound) forms. Three major differences are observed in the crystal structures of TsFDH and CbFDH. Firstly, hole 2 in TsFDH is blocked by helix α20, whereas it is not blocked in CbFDH. Secondly, the sizes of holes 1 and 2 are larger in TsFDH than in CbFDH. Thirdly, Lys287 in TsFDH, which is crucial for the capture of formate and its subsequent delivery to the active site, is an alanine in CbFDH. A computational simulation suggested that the higher CO 2 -reducing activity of TsFDH is owing to its lower free-energy barrier to CO 2 reduction than in CbFDH." @default.
• W2017349714 created "2016-06-24" @default.
• W2017349714 creator A5005894578 @default.
• W2017349714 creator A5007081672 @default.
• W2017349714 creator A5023935515 @default.
• W2017349714 creator A5025344213 @default.
• W2017349714 creator A5032095282 @default.
• W2017349714 creator A5035871875 @default.
• W2017349714 creator A5038214255 @default.
• W2017349714 creator A5039037935 @default.
• W2017349714 creator A5045298504 @default.
• W2017349714 creator A5049205269 @default.
• W2017349714 creator A5064257798 @default.
• W2017349714 creator A5065991900 @default.
• W2017349714 creator A5083251665 @default.
• W2017349714 date "2015-01-23" @default.
• W2017349714 modified "2023-09-27" @default.
• W2017349714 title "Structural insights into the efficient CO₂-reducing activity of an NAD-dependent formate dehydrogenase from<i>Thiobacillus</i>sp. KNK65MA" @default.
• W2017349714 cites W1505575182 @default.
• W2017349714 cites W1539796472 @default.
• W2017349714 cites W1985169370 @default.
• W2017349714 cites W2013931680 @default.
• W2017349714 cites W2015178709 @default.
• W2017349714 cites W2022696619 @default.
• W2017349714 cites W2022950330 @default.
• W2017349714 cites W2025653718 @default.
• W2017349714 cites W2027408247 @default.
• W2017349714 cites W2030359470 @default.
• W2017349714 cites W2030517878 @default.
• W2017349714 cites W2051506593 @default.
• W2017349714 cites W2057052341 @default.
• W2017349714 cites W2060872117 @default.
• W2017349714 cites W2061230876 @default.
• W2017349714 cites W2062714518 @default.
• W2017349714 cites W2063060974 @default.
• W2017349714 cites W2066611187 @default.
• W2017349714 cites W2077776336 @default.
• W2017349714 cites W2080433515 @default.
• W2017349714 cites W2081479951 @default.
• W2017349714 cites W2086456394 @default.
• W2017349714 cites W2087647114 @default.
• W2017349714 cites W2091901197 @default.
• W2017349714 cites W2112154906 @default.
• W2017349714 cites W2125712194 @default.
• W2017349714 cites W2132262459 @default.
• W2017349714 cites W2137015675 @default.
• W2017349714 cites W2144081223 @default.
• W2017349714 cites W2144500963 @default.
• W2017349714 cites W2151544236 @default.
• W2017349714 cites W2152418086 @default.
• W2017349714 cites W2159211495 @default.
• W2017349714 cites W2160698808 @default.
• W2017349714 cites W2163341755 @default.
• W2017349714 cites W2165039004 @default.
• W2017349714 cites W2180229411 @default.
• W2017349714 cites W2313201192 @default.
• W2017349714 doi "https://doi.org/10.1107/s1399004714025474" @default.
• W2017349714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25664741" @default.
• W2017349714 hasPublicationYear "2015" @default.
• W2017349714 type Work @default.
• W2017349714 sameAs 2017349714 @default.
• W2017349714 citedByCount "21" @default.
• W2017349714 countsByYear W20173497142015 @default.
• W2017349714 countsByYear W20173497142016 @default.
• W2017349714 countsByYear W20173497142017 @default.
• W2017349714 countsByYear W20173497142018 @default.
• W2017349714 countsByYear W20173497142019 @default.
• W2017349714 countsByYear W20173497142020 @default.
• W2017349714 countsByYear W20173497142021 @default.
• W2017349714 countsByYear W20173497142023 @default.
• W2017349714 crossrefType "journal-article" @default.
• W2017349714 hasAuthorship W2017349714A5005894578 @default.
• W2017349714 hasAuthorship W2017349714A5007081672 @default.
• W2017349714 hasAuthorship W2017349714A5023935515 @default.
• W2017349714 hasAuthorship W2017349714A5025344213 @default.
• W2017349714 hasAuthorship W2017349714A5032095282 @default.
• W2017349714 hasAuthorship W2017349714A5035871875 @default.
• W2017349714 hasAuthorship W2017349714A5038214255 @default.
• W2017349714 hasAuthorship W2017349714A5039037935 @default.
• W2017349714 hasAuthorship W2017349714A5045298504 @default.
• W2017349714 hasAuthorship W2017349714A5049205269 @default.
• W2017349714 hasAuthorship W2017349714A5064257798 @default.
• W2017349714 hasAuthorship W2017349714A5065991900 @default.
• W2017349714 hasAuthorship W2017349714A5083251665 @default.
• W2017349714 hasConcept C161790260 @default.
• W2017349714 hasConcept C178790620 @default.
• W2017349714 hasConcept C181199279 @default.
• W2017349714 hasConcept C183688256 @default.
• W2017349714 hasConcept C185592680 @default.
• W2017349714 hasConcept C186423591 @default.
• W2017349714 hasConcept C199873434 @default.
• W2017349714 hasConcept C2778428456 @default.
• W2017349714 hasConcept C2780178953 @default.
• W2017349714 hasConcept C41183919 @default.
• W2017349714 hasConcept C55493867 @default.
• W2017349714 hasConcept C71240020 @default.
• W2017349714 hasConcept C75520062 @default.
• W2017349714 hasConceptScore W2017349714C161790260 @default.

• next