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- W2017368445 abstract "0.018); however, higher TNFa concentrations at baseline correlated with lower vedolizumab concentrations at week 6 (Adjusted R2= 0.87, p-value 0.01). Conclusions: While traditional markers of inflammation did not correlate with response to therapy with vedolizumab, sMAdCAM-1 appears to be a possible marker of response to therapy. Further investigations into the etiology underlying the presence of sMAdCAM-1 may help further elucidate the pharmacodynamics and mechanism of action of vedolizumab. Validation in a larger cohort of patients is ongoing." @default.
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- W2017368445 date "2015-04-01" @default.
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- W2017368445 title "536 Non-Trough IFX Concentrations Reliably Predict Trough Levels and Accelerate Dose-Adjustment in Crohn's Disease" @default.
- W2017368445 doi "https://doi.org/10.1016/s0016-5085(15)30368-1" @default.
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