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• W2017377003 abstract "Abstract 1. 1. The bile salts taurocholate and taurodeoxycholate affect the glucose metabolism of adult cestodes Hymenolepis diminuta and H. citelli . 2. 2. When worms were incubated in glucose in the absence of bile salts, H. citelli maintained a higher internal level of free glucose and incorporated twice as much glucose into glycogen than did H. diminuta . Of the glucose metabolized into succinate by H. citelli , 90 per cent came from the exogenous glucose as compared to 80 per cent with H. diminuta . 3. 3. Taurocholate had no effect on glucose metabolism of H. diminuta , but caused a 21 per cent reduction of the internal free glucose level and a 33 per cent reduction in the amount of glucose incorporated into glycogen in H. citelli . 4. 4. Taurodeoxycholate reduced the free pool glucose levels in H. diminuta by 30 per cent and glucose incorporation into glycogen by 50 per cent. The amount of succinate produced was not affected, but the metabolism of exogenously supplied glucose into succinate dropped from 80 to 60 per cent. 5. 5. Taurodeoxycholate caused a 50 per cent decrease in glucose free pool levels in H. citelli and an 80 per cent reduction of glucose incorporation into glycogen. The amount of succinate produced was reduced slightly with the amount of exogenous glucose metabolized into succinate dropping from 90 to 60 per cent. 6. 6. Radioactive taurocholate was not taken up by H. diminuta in vitro , nor were bile salts detected in worm tissue assayed by several procedures. 7. 7. From these results we concluded that the action of bile salts was on the surface of the worm rather than on some internal metabolic process. These data provide additional evidence for the importance of bile salts in the host-parasite relationship." @default.
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• W2017377003 date "1971-12-01" @default.
• W2017377003 modified "2023-09-30" @default.
• W2017377003 title "The effect of bile salts on the carbohydrate metabolism of two species of hymenolepidid cestodes" @default.
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• W2017377003 doi "https://doi.org/10.1016/0305-0491(71)90044-7" @default.
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