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- W2017382951 abstract "[reaction: see text] A novel method for achieving the desired regioselective reduction of the N-1 azido group on a tetraazidoneamine has been developed that leads to the synthesis of both kanamycin and neomycin class antibiotics bearing N-1 modification. Both classes of aminoglycosides are active against aminoglycoside-resistant bacteria carrying APH(3')-I and AAC(6')/APH(2'')." @default.
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- W2017382951 date "2005-06-11" @default.
- W2017382951 modified "2023-09-25" @default.
- W2017382951 title "Tuning the Regioselectivity of the Staudinger Reaction for the Facile Synthesis of Kanamycin and Neomycin Class Antibiotics with N-1 Modification" @default.
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- W2017382951 doi "https://doi.org/10.1021/ol051045d" @default.
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