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- W2017386951 abstract "Abstract Anabolic agents used in animal production can be classified according to their biological activity into compounds with oestrogenic, androgenic and gestagenic activity and according to the structure into endogeneous steroids, extraneous steroids and non-steroidal compounds. Metabolism of endogenous steroids is well established, a major principle being the formation of biologically less active metabolites, whilst the metabolism is not yet fully understood for non-endogenous steroids. Differences between compounds exist and it can be assumed that those with a high oral activity are only to a small extent biodegraded. Tissue residues of anabolic steroids can be expected in the ng/g to pg/g range. By using radioimmunoassay techniques, these low level residues and the naturally occurring tissue-concentration of endogenous steroids can be quantitated. Depending on the. animal and the tissue, endogenous steroids exhibit large variations. Oestrone was > 2 ng/g in muscle from a pregnant cow and, like oestradiol-17β, generally 300 ng/g in pregnant cows and 17 and 6 ng/g in non-pregnant heifers and calves respectively. After implantation of 20 mg oestradiol-17β combined with 200 mg testosterone or progesterone into veal-calves 70–77 days before slaughter the oestrogen-tissue concentrations were" @default.
- W2017386951 created "2016-06-24" @default.
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- W2017386951 date "1979-07-01" @default.
- W2017386951 modified "2023-09-26" @default.
- W2017386951 title "Aspects on the formation and detection of tissue levels of anabolic steroids in domestic animals" @default.
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- W2017386951 doi "https://doi.org/10.1016/0022-4731(79)90030-x" @default.
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