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• W2017393239 startingPage "270" @default.
• W2017393239 abstract "Thoracoabdominal aneurysm (TA) is a pathology that involves the enlargement of the aortic diameter in the inferior descending thoracic aorta and has risk factors including aortic dissection, aortitis or connective tissue disorders. Abnormal flow patterns and haemodynamic stress on the diseased aortic wall are thought to play an important role in the development of this pathology and the internal wall stress has proved to be more reliable as a predictor of rupture than the maximum diameter for abdominal aortic aneurysms; but this assumption has not been validated yet for aneurysms involving the thoracic aorta. In the present study, three patients with TAs of different maximum diameters were scanned using magnetic resonance imaging (MRI) techniques. Realistic models of the aneurysms were reconstructed from the in vivo MRI data acquired from the patients, and subject-specific flow conditions were applied as boundary conditions. The wall and thrombus were modelled as hyperelastic materials and their properties were derived from the literature. A normal descending aorta was also simulated to provide data for comparison. Fully coupled fluid–solid interaction (FSI) simulations as well as solid static simulations were performed using ADINA 8.2. The results show that the wall stress distribution and its magnitude are strongly dependent on the 3-D shape of the aneurysm and the distribution of thrombus. Maximum wall stresses in all TA models are higher than in the normal aorta, and values of maximum wall stress are not directly related to the maximum aneurysm diameter. Comparisons between the FSI and solid static simulation results showed no significant difference in maximum wall stress, supporting those previous studies which found that FSI simulations were not necessary for wall stress prediction." @default.
• W2017393239 created "2016-06-24" @default.
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• W2017393239 creator A5054301083 @default.
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• W2017393239 date "2008-02-01" @default.
• W2017393239 modified "2023-09-27" @default.
• W2017393239 title "Fluid–solid interaction simulation of flow and stress pattern in thoracoabdominal aneurysms: A patient-specific study" @default.
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• W2017393239 doi "https://doi.org/10.1016/j.jfluidstructs.2007.08.005" @default.
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