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- W2017399103 abstract "In the present study, some naphthalene derivatives have been synthesized by incorporating azetidinyl and thiazolidinyl moieties at its α- or β-positions such as α-(3-chloro-2-oxo-4-substituted)aryl-1-azetidinyl)naphthalenes 6–10, α-((substituted)aryl-4-oxo-1,3-thiazolidin-3-yl)naphthalenes 11–15, β-(3-chloro-2-oxo-4-substituted aryl-1-azetidinyl)naphthalenes 21–25, and β-(substituted aryl-4-oxo-1,3-thiazolidin-3-yl)naphthalenes 26–30. These compounds have also been screened for acute toxicity and anti-inflammatory and analgesic activities. Compounds which showed better anti-inflammatory and analgesic activities were also examined for their ulcerogenic liability and underwent a cyclooxygenase assay. Two compounds, 12 and 28, were found to exhibit potent anti-inflammatory activity as compared to the standard drugs phenylbutazone and naproxen." @default.
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- W2017399103 date "2006-03-01" @default.
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- W2017399103 title "A Study of Anti-inflammatory Activity of Some Novel α-Amino Naphthalene and β-Amino Naphthalene Derivatives" @default.
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- W2017399103 doi "https://doi.org/10.1002/ardp.200500215" @default.
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