FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017399460> ?p ?o ?g. }

• W2017399460 endingPage "302" @default.
• W2017399460 startingPage "297" @default.
• W2017399460 abstract "McArdle disease (MD) is a metabolic myopathy due to myophosphorylase deficiency, which leads to a severe limitation in the rate of adenosine triphosphate (ATP) resynthesis. Compensatory flux through the myoadenylate deaminase > > xanthine oxidase pathway should result in higher oxidative stress in skeletal muscle; however, oxidative stress and nuclear factor erythroid 2-related factor 2 (Nrf2) mediated antioxidant response cascade in MD patients have not yet been examined. We show that MD patients have elevated muscle protein carbonyls and 4-hydroxynonenal (4-HNE) in comparison with healthy, age and activity matched controls (P < 0.05). Nuclear abundance of Nrf2 and Nrf2-antioxidant response element (ARE) binding was also higher in MD patients compared with controls (P < 0.05). The expressions of Nrf2 target genes were also higher in MD patients vs. controls. These observations suggest that MD patients experience elevated levels of oxidative stress, and that the Nrf2-mediated antioxidant response cascade is up-regulated in skeletal muscle to compensate." @default.
• W2017399460 created "2016-06-24" @default.
• W2017399460 creator A5008660174 @default.
• W2017399460 creator A5020091796 @default.
• W2017399460 creator A5036093733 @default.
• W2017399460 creator A5036460871 @default.
• W2017399460 creator A5049073072 @default.
• W2017399460 creator A5058362778 @default.
• W2017399460 date "2013-11-01" @default.
• W2017399460 modified "2023-10-13" @default.
• W2017399460 title "Oxidative stress and Nrf2 signaling in McArdle disease" @default.
• W2017399460 cites W1490256361 @default.
• W2017399460 cites W1942154378 @default.
• W2017399460 cites W197061316 @default.
• W2017399460 cites W1972495012 @default.
• W2017399460 cites W1972672156 @default.
• W2017399460 cites W1979646954 @default.
• W2017399460 cites W1987910700 @default.
• W2017399460 cites W1989305503 @default.
• W2017399460 cites W2000017694 @default.
• W2017399460 cites W2006311748 @default.
• W2017399460 cites W2007021621 @default.
• W2017399460 cites W2012300541 @default.
• W2017399460 cites W2019544413 @default.
• W2017399460 cites W2028169098 @default.
• W2017399460 cites W2041433343 @default.
• W2017399460 cites W2044024911 @default.
• W2017399460 cites W2044560810 @default.
• W2017399460 cites W2052085642 @default.
• W2017399460 cites W2058283135 @default.
• W2017399460 cites W2074138632 @default.
• W2017399460 cites W2081478178 @default.
• W2017399460 cites W2084644507 @default.
• W2017399460 cites W2086720703 @default.
• W2017399460 cites W2092160704 @default.
• W2017399460 cites W2097146819 @default.
• W2017399460 cites W2102408100 @default.
• W2017399460 cites W2128705476 @default.
• W2017399460 cites W2135277493 @default.
• W2017399460 cites W2161220011 @default.
• W2017399460 doi "https://doi.org/10.1016/j.ymgme.2013.06.022" @default.
• W2017399460 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23906480" @default.
• W2017399460 hasPublicationYear "2013" @default.
• W2017399460 type Work @default.
• W2017399460 sameAs 2017399460 @default.
• W2017399460 citedByCount "24" @default.
• W2017399460 countsByYear W20173994602014 @default.
• W2017399460 countsByYear W20173994602015 @default.
• W2017399460 countsByYear W20173994602016 @default.
• W2017399460 countsByYear W20173994602017 @default.
• W2017399460 countsByYear W20173994602018 @default.
• W2017399460 countsByYear W20173994602019 @default.
• W2017399460 countsByYear W20173994602020 @default.
• W2017399460 countsByYear W20173994602021 @default.
• W2017399460 countsByYear W20173994602022 @default.
• W2017399460 countsByYear W20173994602023 @default.
• W2017399460 crossrefType "journal-article" @default.
• W2017399460 hasAuthorship W2017399460A5008660174 @default.
• W2017399460 hasAuthorship W2017399460A5020091796 @default.
• W2017399460 hasAuthorship W2017399460A5036093733 @default.
• W2017399460 hasAuthorship W2017399460A5036460871 @default.
• W2017399460 hasAuthorship W2017399460A5049073072 @default.
• W2017399460 hasAuthorship W2017399460A5058362778 @default.
• W2017399460 hasConcept C104317684 @default.
• W2017399460 hasConcept C126322002 @default.
• W2017399460 hasConcept C134018914 @default.
• W2017399460 hasConcept C181199279 @default.
• W2017399460 hasConcept C185592680 @default.
• W2017399460 hasConcept C2776151105 @default.
• W2017399460 hasConcept C2776529522 @default.
• W2017399460 hasConcept C2777300911 @default.
• W2017399460 hasConcept C2778004101 @default.
• W2017399460 hasConcept C2778102346 @default.
• W2017399460 hasConcept C2779564974 @default.
• W2017399460 hasConcept C2779959927 @default.
• W2017399460 hasConcept C55493867 @default.
• W2017399460 hasConcept C57600042 @default.
• W2017399460 hasConcept C71924100 @default.
• W2017399460 hasConcept C86339819 @default.
• W2017399460 hasConceptScore W2017399460C104317684 @default.
• W2017399460 hasConceptScore W2017399460C126322002 @default.
• W2017399460 hasConceptScore W2017399460C134018914 @default.
• W2017399460 hasConceptScore W2017399460C181199279 @default.
• W2017399460 hasConceptScore W2017399460C185592680 @default.
• W2017399460 hasConceptScore W2017399460C2776151105 @default.
• W2017399460 hasConceptScore W2017399460C2776529522 @default.
• W2017399460 hasConceptScore W2017399460C2777300911 @default.
• W2017399460 hasConceptScore W2017399460C2778004101 @default.
• W2017399460 hasConceptScore W2017399460C2778102346 @default.
• W2017399460 hasConceptScore W2017399460C2779564974 @default.
• W2017399460 hasConceptScore W2017399460C2779959927 @default.
• W2017399460 hasConceptScore W2017399460C55493867 @default.
• W2017399460 hasConceptScore W2017399460C57600042 @default.
• W2017399460 hasConceptScore W2017399460C71924100 @default.
• W2017399460 hasConceptScore W2017399460C86339819 @default.
• W2017399460 hasIssue "3" @default.
• W2017399460 hasLocation W20173994601 @default.
• W2017399460 hasLocation W20173994602 @default.

• next