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• W2017403940 abstract "Significance A comparative analysis of conserved domain fragments amplified from nonribosomal peptide and polyketide-type gene clusters present in diverse soil microbiomes revealed a link between soil type, species composition, and biosynthetic richness, as well as an unexpected conservation of the meta-secondary metabolome present within microbiomes from similar soil types. Although the functional consequences of these enrichment patterns is not yet clear, it suggests that similar soil types contain functionally related collections of secondary metabolites that likely play conserved roles in the ecology of these soils. This work provides a model for the large-scale extension of molecular phylogenetic-type analyses directly to the study, characterization, and comparison of secondary metabolite biosynthetic gene clusters that remain hidden in diverse soil microbiomes." @default.
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• W2017403940 date "2014-02-18" @default.
• W2017403940 modified "2023-10-12" @default.
• W2017403940 title "Chemical-biogeographic survey of secondary metabolism in soil" @default.
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• W2017403940 doi "https://doi.org/10.1073/pnas.1318021111" @default.
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