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- W2017407903 abstract "ABSTRACT Growth of Bartonella henselae is strongly heme dependent, and B. henselae is unable to synthesize heme itself. At least five outer membrane-associated proteins from B. henselae bind hemin, including the 31-kDa protein designated Pap31. The gene of this protein was heterologously expressed in Escherichia coli M15(pREP4) and detected with monoclonal antibodies in the outer membrane fraction. Complementation of the hemA -deficient mutant E. coli K-12 EB53 ( aroB tsx malT hemA ) with pap31 demonstrated that this protein is involved in heme acquisition and may be an important virulence factor in the pathogenesis of B. henselae ." @default.
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- W2017407903 date "2003-03-01" @default.
- W2017407903 modified "2023-10-06" @default.
- W2017407903 title "Hemin Binding, Functional Expression, and Complementation Analysis of Pap 31 from Bartonella henselae" @default.
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- W2017407903 doi "https://doi.org/10.1128/jb.185.5.1739-1744.2003" @default.
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