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• W2017423419 endingPage "17" @default.
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• W2017423419 abstract "Visual cortical neurons exhibit a high degree of response selectivity and are grouped into small columns according to their response preferences. The columns are located at regularly spaced intervals covering the whole cortical representation of the visual field with a modular system of feature-selective neurons. The selectivity of these cells and their modular arrangement is thought to emerge from interactions in the network of specific intracortical and thalamocortical connections. Understanding the ontogenesis of this complex structure and contributions of intrinsic and extrinsic, experience-dependent mechanisms during cortical development can provide new insights into the way the visual cortex processes information about the environment. Available data about the development of connections and response properties in the visual cortex suggest that maturation proceeds in two distinct steps. In the first phase, mechanisms inherent to the cortex establish a crude framework of interconnected neural modules which exhibit the basic but still immature traits of the adult state. Relevant mechanisms in this phase are assumed to consist of molecular cues and patterns of spontaneous neural activity in cortical and corticothalamic interconnections. In a second phase, the primordial layout becomes refined under the control of visual experience establishing a fine-tuned network of connections and mature response properties." @default.
• W2017423419 created "2016-06-24" @default.
• W2017423419 creator A5005292748 @default.
• W2017423419 creator A5044809786 @default.
• W2017423419 creator A5079294653 @default.
• W2017423419 date "1999-10-01" @default.
• W2017423419 modified "2023-09-27" @default.
• W2017423419 title "Matching the modules: Cortical maps and long-range intrinsic connections in visual cortex during development" @default.
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• W2017423419 doi "https://doi.org/10.1002/(sici)1097-4695(199910)41:1<10::aid-neu3>3.0.co;2-l" @default.
• W2017423419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10504187" @default.
• W2017423419 hasPublicationYear "1999" @default.
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