Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017425838> ?p ?o ?g. }
- W2017425838 endingPage "450" @default.
- W2017425838 startingPage "446" @default.
- W2017425838 abstract "Cancer cachexia is a complex metabolic syndrome that manifests as a progressive wasting disorder. Recent findings have substantially improved our understanding of this unique entity shedding light on a potentially significant and overlooked morbidity in the form of cardiac functional changes that may occur in tandem with cachexia. Moreover, recent technological advances, such as with the application of metabolomic analysis, have yielded a better understanding of the metabolic changes that accompany this condition.Recent evidence from murine studies indicates that the skeletal muscle wasting in cancer cachexia may be accompanied by cardiac muscle wasting. This decreased heart weight is accompanied by functional cardiac changes, which are suggestive of congestive heart failure. In addition, metabolomic analysis of body fluids and tissues distinguishes cancer cachexia's unique metabolic fingerprint as a separate entity, different from healthy controls, tumor burden, caloric restriction, and aging. It also gives insight into the metabolic changes that occur in the affected tissues such as the Warburg effect that is not often described in muscle.Translational investigations into potential cardiac malfunction in cancer patients and metabolomic analyses of patients' sera and tissues are warranted to determine whether these changes are upheld in humans." @default.
- W2017425838 created "2016-06-24" @default.
- W2017425838 creator A5000752691 @default.
- W2017425838 creator A5076448579 @default.
- W2017425838 creator A5090338744 @default.
- W2017425838 date "2012-12-01" @default.
- W2017425838 modified "2023-10-06" @default.
- W2017425838 title "Translational implications of novel findings in cancer cachexia" @default.
- W2017425838 cites W1919840413 @default.
- W2017425838 cites W1971875639 @default.
- W2017425838 cites W1973298339 @default.
- W2017425838 cites W1976397063 @default.
- W2017425838 cites W1979654624 @default.
- W2017425838 cites W1982199511 @default.
- W2017425838 cites W1988793551 @default.
- W2017425838 cites W2003064100 @default.
- W2017425838 cites W2008622683 @default.
- W2017425838 cites W2008869575 @default.
- W2017425838 cites W2015446840 @default.
- W2017425838 cites W2038469310 @default.
- W2017425838 cites W2048288697 @default.
- W2017425838 cites W2054261511 @default.
- W2017425838 cites W2058186388 @default.
- W2017425838 cites W2061504786 @default.
- W2017425838 cites W2066992126 @default.
- W2017425838 cites W2072451742 @default.
- W2017425838 cites W2072805739 @default.
- W2017425838 cites W2074756934 @default.
- W2017425838 cites W2077415753 @default.
- W2017425838 cites W2081903080 @default.
- W2017425838 cites W2105924666 @default.
- W2017425838 cites W2135059059 @default.
- W2017425838 cites W2137590405 @default.
- W2017425838 cites W2142153547 @default.
- W2017425838 cites W2151283204 @default.
- W2017425838 cites W2153221436 @default.
- W2017425838 cites W2155289323 @default.
- W2017425838 cites W2168257591 @default.
- W2017425838 cites W2234954315 @default.
- W2017425838 cites W2614795676 @default.
- W2017425838 cites W4231548689 @default.
- W2017425838 doi "https://doi.org/10.1097/spc.0b013e328359b695" @default.
- W2017425838 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23123818" @default.
- W2017425838 hasPublicationYear "2012" @default.
- W2017425838 type Work @default.
- W2017425838 sameAs 2017425838 @default.
- W2017425838 citedByCount "11" @default.
- W2017425838 countsByYear W20174258382014 @default.
- W2017425838 countsByYear W20174258382015 @default.
- W2017425838 countsByYear W20174258382017 @default.
- W2017425838 countsByYear W20174258382018 @default.
- W2017425838 countsByYear W20174258382022 @default.
- W2017425838 crossrefType "journal-article" @default.
- W2017425838 hasAuthorship W2017425838A5000752691 @default.
- W2017425838 hasAuthorship W2017425838A5076448579 @default.
- W2017425838 hasAuthorship W2017425838A5090338744 @default.
- W2017425838 hasConcept C121608353 @default.
- W2017425838 hasConcept C126322002 @default.
- W2017425838 hasConcept C21565614 @default.
- W2017425838 hasConcept C2777704314 @default.
- W2017425838 hasConcept C2778198053 @default.
- W2017425838 hasConcept C2778996579 @default.
- W2017425838 hasConcept C2779764123 @default.
- W2017425838 hasConcept C2779959927 @default.
- W2017425838 hasConcept C2911126609 @default.
- W2017425838 hasConcept C3020092424 @default.
- W2017425838 hasConcept C60644358 @default.
- W2017425838 hasConcept C71924100 @default.
- W2017425838 hasConcept C86803240 @default.
- W2017425838 hasConceptScore W2017425838C121608353 @default.
- W2017425838 hasConceptScore W2017425838C126322002 @default.
- W2017425838 hasConceptScore W2017425838C21565614 @default.
- W2017425838 hasConceptScore W2017425838C2777704314 @default.
- W2017425838 hasConceptScore W2017425838C2778198053 @default.
- W2017425838 hasConceptScore W2017425838C2778996579 @default.
- W2017425838 hasConceptScore W2017425838C2779764123 @default.
- W2017425838 hasConceptScore W2017425838C2779959927 @default.
- W2017425838 hasConceptScore W2017425838C2911126609 @default.
- W2017425838 hasConceptScore W2017425838C3020092424 @default.
- W2017425838 hasConceptScore W2017425838C60644358 @default.
- W2017425838 hasConceptScore W2017425838C71924100 @default.
- W2017425838 hasConceptScore W2017425838C86803240 @default.
- W2017425838 hasIssue "4" @default.
- W2017425838 hasLocation W20174258381 @default.
- W2017425838 hasLocation W20174258382 @default.
- W2017425838 hasOpenAccess W2017425838 @default.
- W2017425838 hasPrimaryLocation W20174258381 @default.
- W2017425838 hasRelatedWork W1955421468 @default.
- W2017425838 hasRelatedWork W1989980876 @default.
- W2017425838 hasRelatedWork W2040510149 @default.
- W2017425838 hasRelatedWork W2282725908 @default.
- W2017425838 hasRelatedWork W2283385184 @default.
- W2017425838 hasRelatedWork W2314840099 @default.
- W2017425838 hasRelatedWork W2405634401 @default.
- W2017425838 hasRelatedWork W2972845984 @default.
- W2017425838 hasRelatedWork W38212549 @default.
- W2017425838 hasRelatedWork W2684438593 @default.
- W2017425838 hasVolume "6" @default.