Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017439912> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2017439912 endingPage "1269" @default.
- W2017439912 startingPage "1267" @default.
- W2017439912 abstract "This work reveals two biochemical effects of hydrogen peroxide treatment on hemoglobin, myoglobin, and cytochrome c. First, these heme proteins rapidly formed covalently crosslinked dimers and polymers detectable by detergent gel electrophoresis. Second, when treated in the presence of radioactive benzo[a]pyrene or 17β-estradiol, the heme proteins became covalently labeled. Nonheme proteins exhibited both cross-linking and radioactive labeling upon peroxide treatment in the presence but not the absence of heme protein or free hemin. Benzoyl peroxide or glucose and glucose oxidase effectively replaced direct addition of hydrogen peroxide. These results indicate that adventitious peroxidase activity expressed by oxygen carrying and electron transport proteins yields active oxygen species that can damage these heme proteins and nearby macromolecules, a possible biochemical mechanism for the lethal and other deleterious intracellular effects of perioxide." @default.
- W2017439912 created "2016-06-24" @default.
- W2017439912 creator A5002699848 @default.
- W2017439912 creator A5045593549 @default.
- W2017439912 creator A5045859373 @default.
- W2017439912 date "1977-07-01" @default.
- W2017439912 modified "2023-09-27" @default.
- W2017439912 title "Peroxidase-catalyzed irreversible binding of morphine to protein" @default.
- W2017439912 cites W1979385488 @default.
- W2017439912 cites W1981286144 @default.
- W2017439912 cites W2036291213 @default.
- W2017439912 cites W2053815177 @default.
- W2017439912 cites W2061388923 @default.
- W2017439912 cites W2062569241 @default.
- W2017439912 cites W2067893259 @default.
- W2017439912 cites W2087001288 @default.
- W2017439912 cites W2413905329 @default.
- W2017439912 cites W2426588295 @default.
- W2017439912 doi "https://doi.org/10.1016/0006-2952(77)90118-6" @default.
- W2017439912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/880273" @default.
- W2017439912 hasPublicationYear "1977" @default.
- W2017439912 type Work @default.
- W2017439912 sameAs 2017439912 @default.
- W2017439912 citedByCount "5" @default.
- W2017439912 crossrefType "journal-article" @default.
- W2017439912 hasAuthorship W2017439912A5002699848 @default.
- W2017439912 hasAuthorship W2017439912A5045593549 @default.
- W2017439912 hasAuthorship W2017439912A5045859373 @default.
- W2017439912 hasConcept C162008176 @default.
- W2017439912 hasConcept C178790620 @default.
- W2017439912 hasConcept C180577832 @default.
- W2017439912 hasConcept C181199279 @default.
- W2017439912 hasConcept C185592680 @default.
- W2017439912 hasConcept C201956729 @default.
- W2017439912 hasConcept C20705724 @default.
- W2017439912 hasConcept C2776217839 @default.
- W2017439912 hasConcept C2777197210 @default.
- W2017439912 hasConcept C2777676563 @default.
- W2017439912 hasConcept C2777723881 @default.
- W2017439912 hasConcept C2778063876 @default.
- W2017439912 hasConcept C2778417259 @default.
- W2017439912 hasConcept C2778917026 @default.
- W2017439912 hasConcept C2778951431 @default.
- W2017439912 hasConcept C2779480358 @default.
- W2017439912 hasConcept C2781048764 @default.
- W2017439912 hasConcept C533411734 @default.
- W2017439912 hasConcept C55493867 @default.
- W2017439912 hasConceptScore W2017439912C162008176 @default.
- W2017439912 hasConceptScore W2017439912C178790620 @default.
- W2017439912 hasConceptScore W2017439912C180577832 @default.
- W2017439912 hasConceptScore W2017439912C181199279 @default.
- W2017439912 hasConceptScore W2017439912C185592680 @default.
- W2017439912 hasConceptScore W2017439912C201956729 @default.
- W2017439912 hasConceptScore W2017439912C20705724 @default.
- W2017439912 hasConceptScore W2017439912C2776217839 @default.
- W2017439912 hasConceptScore W2017439912C2777197210 @default.
- W2017439912 hasConceptScore W2017439912C2777676563 @default.
- W2017439912 hasConceptScore W2017439912C2777723881 @default.
- W2017439912 hasConceptScore W2017439912C2778063876 @default.
- W2017439912 hasConceptScore W2017439912C2778417259 @default.
- W2017439912 hasConceptScore W2017439912C2778917026 @default.
- W2017439912 hasConceptScore W2017439912C2778951431 @default.
- W2017439912 hasConceptScore W2017439912C2779480358 @default.
- W2017439912 hasConceptScore W2017439912C2781048764 @default.
- W2017439912 hasConceptScore W2017439912C533411734 @default.
- W2017439912 hasConceptScore W2017439912C55493867 @default.
- W2017439912 hasIssue "13" @default.
- W2017439912 hasLocation W20174399121 @default.
- W2017439912 hasLocation W20174399122 @default.
- W2017439912 hasOpenAccess W2017439912 @default.
- W2017439912 hasPrimaryLocation W20174399121 @default.
- W2017439912 hasRelatedWork W1567786336 @default.
- W2017439912 hasRelatedWork W1966316125 @default.
- W2017439912 hasRelatedWork W1989262363 @default.
- W2017439912 hasRelatedWork W2015572850 @default.
- W2017439912 hasRelatedWork W2026591369 @default.
- W2017439912 hasRelatedWork W2078386248 @default.
- W2017439912 hasRelatedWork W2098131246 @default.
- W2017439912 hasRelatedWork W2945656927 @default.
- W2017439912 hasRelatedWork W4214599998 @default.
- W2017439912 hasRelatedWork W2044583361 @default.
- W2017439912 hasVolume "26" @default.
- W2017439912 isParatext "false" @default.
- W2017439912 isRetracted "false" @default.
- W2017439912 magId "2017439912" @default.
- W2017439912 workType "article" @default.