FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017441682> ?p ?o ?g. }

• W2017441682 endingPage "1172" @default.
• W2017441682 startingPage "1167" @default.
• W2017441682 abstract "Rat colon neoplasms are distributed 60% in the distal colon (DC) and 40% in the proximal colon (PC), similar to distribution of colon cancers in the industrialized world. The effects of chemopreventive agents that affect colon tumor incidence on the distribution of colon tumors were studied.Colon tumor distribution, numbers, and volumes were measured in the DC and PC of rats administered azoxymethane (15 mg/kg subcutaneously 2x) as an initiating agent and fed diets containing various chemopreventive agents.In control rats, azoxymethane-induced tumor incidence in the DC exceeded that in the PC, but tumor volume was greater in the PC than the DC. Ellagic acid showed no chemopreventive effect and maintained the PC-DC colon tumor gradient. Oltipraz, a modestly effective chemopreventive agent, principally reduced the incidence of DC tumors. DL-d-difluoromethylornithine also greatly altered tumor number in the DC compared with the PC. In contrast, piroxicam (400 ppm) reduced PC tumors by 82% but DC tumors only by 57%. With all regimens, tumor volume remained greater in the PC than the DC.Chemopreventive agents have a selective regional effect on colon tumorigenesis in the rat. Elucidation of the mechanism for these differences may help clarify the modes of action of chemopreventive agents in colon cancer." @default.
• W2017441682 created "2016-06-24" @default.
• W2017441682 creator A5004691943 @default.
• W2017441682 creator A5024627457 @default.
• W2017441682 creator A5058569549 @default.
• W2017441682 creator A5060398966 @default.
• W2017441682 creator A5085524072 @default.
• W2017441682 date "1995-10-01" @default.
• W2017441682 modified "2023-09-25" @default.
• W2017441682 title "Regional chemoprevention of carcinogen-induced tumors in rat colon" @default.
• W2017441682 cites W1556877038 @default.
• W2017441682 cites W1561321452 @default.
• W2017441682 cites W1586713220 @default.
• W2017441682 cites W1596781203 @default.
• W2017441682 cites W1631446185 @default.
• W2017441682 cites W1925690329 @default.
• W2017441682 cites W1967914030 @default.
• W2017441682 cites W2026260356 @default.
• W2017441682 cites W2026831500 @default.
• W2017441682 cites W2030948649 @default.
• W2017441682 cites W2032122995 @default.
• W2017441682 cites W2036616336 @default.
• W2017441682 cites W2045061052 @default.
• W2017441682 cites W2066681384 @default.
• W2017441682 cites W2080907168 @default.
• W2017441682 cites W2084954009 @default.
• W2017441682 cites W2110575387 @default.
• W2017441682 cites W2113491538 @default.
• W2017441682 cites W2138011982 @default.
• W2017441682 cites W2138432364 @default.
• W2017441682 cites W2140979026 @default.
• W2017441682 cites W2161356660 @default.
• W2017441682 cites W2167092337 @default.
• W2017441682 cites W2177197667 @default.
• W2017441682 cites W2285515723 @default.
• W2017441682 cites W2293750114 @default.
• W2017441682 cites W2295142739 @default.
• W2017441682 cites W2312794843 @default.
• W2017441682 doi "https://doi.org/10.1016/0016-5085(95)90575-8" @default.
• W2017441682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7557082" @default.
• W2017441682 hasPublicationYear "1995" @default.
• W2017441682 type Work @default.
• W2017441682 sameAs 2017441682 @default.
• W2017441682 citedByCount "34" @default.
• W2017441682 countsByYear W20174416822012 @default.
• W2017441682 countsByYear W20174416822017 @default.
• W2017441682 countsByYear W20174416822018 @default.
• W2017441682 crossrefType "journal-article" @default.
• W2017441682 hasAuthorship W2017441682A5004691943 @default.
• W2017441682 hasAuthorship W2017441682A5024627457 @default.
• W2017441682 hasAuthorship W2017441682A5058569549 @default.
• W2017441682 hasAuthorship W2017441682A5060398966 @default.
• W2017441682 hasAuthorship W2017441682A5085524072 @default.
• W2017441682 hasConcept C110121322 @default.
• W2017441682 hasConcept C114246631 @default.
• W2017441682 hasConcept C121608353 @default.
• W2017441682 hasConcept C126322002 @default.
• W2017441682 hasConcept C134306372 @default.
• W2017441682 hasConcept C185592680 @default.
• W2017441682 hasConcept C2778452354 @default.
• W2017441682 hasConcept C2779107934 @default.
• W2017441682 hasConcept C33923547 @default.
• W2017441682 hasConcept C502942594 @default.
• W2017441682 hasConcept C526805850 @default.
• W2017441682 hasConcept C55493867 @default.
• W2017441682 hasConcept C555283112 @default.
• W2017441682 hasConcept C71924100 @default.
• W2017441682 hasConcept C90924648 @default.
• W2017441682 hasConcept C98274493 @default.
• W2017441682 hasConceptScore W2017441682C110121322 @default.
• W2017441682 hasConceptScore W2017441682C114246631 @default.
• W2017441682 hasConceptScore W2017441682C121608353 @default.
• W2017441682 hasConceptScore W2017441682C126322002 @default.
• W2017441682 hasConceptScore W2017441682C134306372 @default.
• W2017441682 hasConceptScore W2017441682C185592680 @default.
• W2017441682 hasConceptScore W2017441682C2778452354 @default.
• W2017441682 hasConceptScore W2017441682C2779107934 @default.
• W2017441682 hasConceptScore W2017441682C33923547 @default.
• W2017441682 hasConceptScore W2017441682C502942594 @default.
• W2017441682 hasConceptScore W2017441682C526805850 @default.
• W2017441682 hasConceptScore W2017441682C55493867 @default.
• W2017441682 hasConceptScore W2017441682C555283112 @default.
• W2017441682 hasConceptScore W2017441682C71924100 @default.
• W2017441682 hasConceptScore W2017441682C90924648 @default.
• W2017441682 hasConceptScore W2017441682C98274493 @default.
• W2017441682 hasIssue "4" @default.
• W2017441682 hasLocation W20174416821 @default.
• W2017441682 hasLocation W20174416822 @default.
• W2017441682 hasOpenAccess W2017441682 @default.
• W2017441682 hasPrimaryLocation W20174416821 @default.
• W2017441682 hasRelatedWork W1995499932 @default.
• W2017441682 hasRelatedWork W2027315119 @default.
• W2017441682 hasRelatedWork W2028850353 @default.
• W2017441682 hasRelatedWork W2045161776 @default.
• W2017441682 hasRelatedWork W2100283599 @default.
• W2017441682 hasRelatedWork W2110575387 @default.
• W2017441682 hasRelatedWork W2123961393 @default.
• W2017441682 hasRelatedWork W2893923927 @default.

• next