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- W2017446896 abstract "(18)F-fluoro-2-deoxy-D-glucose PET-computed tomography (CT) has a major clinical impact in oncology not only for diagnostics but also for staging, response assessment, and relapse detection. However, several other PET tracers are needed for a more complete molecular characterization of cancers which has great importance in the era of individualized targeted therapies. PET-CT is an exquisite tool for molecular imaging because it allows detection of nanomolar quantities of tracer molecules targeting different hallmarks of cancer.This article reviews the most recent findings (published in 2010-2011) on the use of molecular imaging for assessing tumour proliferation, apoptosis, growth receptor expression, bone metabolism, and hypoxia.Molecular imaging using PET-CT constitutes a major opportunity in translational research bringing fundamental molecular insights to the clinical area. Such information results invaluable for patient selection and prediction of response to therapy and serves as a crucial diagnostic tool in the era of personalized medicine." @default.
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- W2017446896 date "2012-11-01" @default.
- W2017446896 modified "2023-10-05" @default.
- W2017446896 title "New PET imaging agents in the management of solid cancers" @default.
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- W2017446896 doi "https://doi.org/10.1097/cco.0b013e32835766f7" @default.
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