FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017453407> ?p ?o ?g. }

• W2017453407 endingPage "20" @default.
• W2017453407 startingPage "11" @default.
• W2017453407 abstract "We studied hypertension-associated changes in prejunctional alpha(2) adrenergic receptor (alpha(2)-AR) function using amperometry to monitor in vitro norepinephrine (NE) measured as oxidation currents. Vasoconstriction was measured using video imaging. NE release was induced by electrical stimulation of sympathetic nerves associated with mesenteric arteries (MA) and veins (MV) of sham and DOCA-salt hypertensive rats. NE oxidation currents were larger in DOCA-salt compared to sham MA; there were no differences between currents in sham and DOCA-salt MV. Increases in NE oxidation currents followed a multi-exponential time course in sham MA. In DOCA-salt MA and sham and DOCA-salt MV, the time course was mono-exponential. Yohimbine (alpha(2)-AR antagonist, 1 microM), caused a mono-exponential increase in NE oxidation currents in sham and DOCA-salt MA. Yohimbine increased NE oxidation currents and constrictions more in sham compared to DOCA-salt MA and compared to MV. UK 14,304 (alpha(2)-AR agonist, 1.0 microM), reduced currents less in DOCA-salt MA and sham and DOCA-salt MV compared to sham MA. Prazosin (alpha(1)-AR antagonist, 0.1 microM) did not alter NE oxidation currents. Prazosin inhibited constrictions more in DOCA-salt compared to sham MA and almost completely blocked constrictions in sham and DOCA-salt MV. Prazosin-resistant constrictions in MA were blocked by the P2 receptor antagonist, PPADS (10 microM). Prejunctional alpha(2)-ARs modify NE concentrations near neuroeffector junctions in MA and MV. alpha(2)-AR function is most prominent in MA and is impaired in DOCA-salt MA but not MV. Purinergic transmission predominates in sham MA. NE is the dominant vasoconstrictor in DOCA-salt MA and sham and DOCA-salt MV." @default.
• W2017453407 created "2016-06-24" @default.
• W2017453407 creator A5008183759 @default.
• W2017453407 creator A5053076079 @default.
• W2017453407 creator A5073641507 @default.
• W2017453407 creator A5085256874 @default.
• W2017453407 date "2010-01-01" @default.
• W2017453407 modified "2023-09-25" @default.
• W2017453407 title "Alterations in sympathetic neuroeffector transmission to mesenteric arteries but not veins in DOCA-salt hypertension" @default.
• W2017453407 cites W1480852888 @default.
• W2017453407 cites W1546379901 @default.
• W2017453407 cites W1979889928 @default.
• W2017453407 cites W1985989203 @default.
• W2017453407 cites W1986828570 @default.
• W2017453407 cites W2001858748 @default.
• W2017453407 cites W2007168440 @default.
• W2017453407 cites W2008894210 @default.
• W2017453407 cites W2015052056 @default.
• W2017453407 cites W2015170490 @default.
• W2017453407 cites W2017735702 @default.
• W2017453407 cites W2021348136 @default.
• W2017453407 cites W2028358699 @default.
• W2017453407 cites W2028639895 @default.
• W2017453407 cites W2034609931 @default.
• W2017453407 cites W2038642133 @default.
• W2017453407 cites W2040204113 @default.
• W2017453407 cites W2047298388 @default.
• W2017453407 cites W2055272286 @default.
• W2017453407 cites W2060435183 @default.
• W2017453407 cites W2060620464 @default.
• W2017453407 cites W2061295377 @default.
• W2017453407 cites W2071811579 @default.
• W2017453407 cites W2075580596 @default.
• W2017453407 cites W2076446101 @default.
• W2017453407 cites W2080853193 @default.
• W2017453407 cites W2087569926 @default.
• W2017453407 cites W2093921718 @default.
• W2017453407 cites W2107974693 @default.
• W2017453407 cites W2120732472 @default.
• W2017453407 cites W2123629158 @default.
• W2017453407 cites W2128104176 @default.
• W2017453407 cites W2129953181 @default.
• W2017453407 cites W2134939493 @default.
• W2017453407 cites W2137335941 @default.
• W2017453407 cites W2150569946 @default.
• W2017453407 cites W2161386502 @default.
• W2017453407 cites W2301674354 @default.
• W2017453407 doi "https://doi.org/10.1016/j.autneu.2009.08.008" @default.
• W2017453407 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2903739" @default.
• W2017453407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19914150" @default.
• W2017453407 hasPublicationYear "2010" @default.
• W2017453407 type Work @default.
• W2017453407 sameAs 2017453407 @default.
• W2017453407 citedByCount "25" @default.
• W2017453407 countsByYear W20174534072012 @default.
• W2017453407 countsByYear W20174534072013 @default.
• W2017453407 countsByYear W20174534072014 @default.
• W2017453407 countsByYear W20174534072015 @default.
• W2017453407 countsByYear W20174534072017 @default.
• W2017453407 countsByYear W20174534072018 @default.
• W2017453407 countsByYear W20174534072019 @default.
• W2017453407 countsByYear W20174534072020 @default.
• W2017453407 countsByYear W20174534072021 @default.
• W2017453407 crossrefType "journal-article" @default.
• W2017453407 hasAuthorship W2017453407A5008183759 @default.
• W2017453407 hasAuthorship W2017453407A5053076079 @default.
• W2017453407 hasAuthorship W2017453407A5073641507 @default.
• W2017453407 hasAuthorship W2017453407A5085256874 @default.
• W2017453407 hasBestOaLocation W20174534072 @default.
• W2017453407 hasConcept C120770815 @default.
• W2017453407 hasConcept C126322002 @default.
• W2017453407 hasConcept C134018914 @default.
• W2017453407 hasConcept C170493617 @default.
• W2017453407 hasConcept C185592680 @default.
• W2017453407 hasConcept C1918360 @default.
• W2017453407 hasConcept C24998067 @default.
• W2017453407 hasConcept C2776820930 @default.
• W2017453407 hasConcept C2776885963 @default.
• W2017453407 hasConcept C2777676773 @default.
• W2017453407 hasConcept C2779066535 @default.
• W2017453407 hasConcept C2779961880 @default.
• W2017453407 hasConcept C2780648677 @default.
• W2017453407 hasConcept C2780771799 @default.
• W2017453407 hasConcept C2910296299 @default.
• W2017453407 hasConcept C519063684 @default.
• W2017453407 hasConcept C71924100 @default.
• W2017453407 hasConceptScore W2017453407C120770815 @default.
• W2017453407 hasConceptScore W2017453407C126322002 @default.
• W2017453407 hasConceptScore W2017453407C134018914 @default.
• W2017453407 hasConceptScore W2017453407C170493617 @default.
• W2017453407 hasConceptScore W2017453407C185592680 @default.
• W2017453407 hasConceptScore W2017453407C1918360 @default.
• W2017453407 hasConceptScore W2017453407C24998067 @default.
• W2017453407 hasConceptScore W2017453407C2776820930 @default.
• W2017453407 hasConceptScore W2017453407C2776885963 @default.
• W2017453407 hasConceptScore W2017453407C2777676773 @default.
• W2017453407 hasConceptScore W2017453407C2779066535 @default.
• W2017453407 hasConceptScore W2017453407C2779961880 @default.

• next