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- W2017454918 abstract "To summarize the recent developments concerning the potential viral pathomechanisms and involvement of viruses in Sjögren's syndrome, and to highlight the areas for future research and therapies.Activated IFN-1 pathway plays an important part in the autoimmune disease process of Sjögren's syndrome; therefore, several therapies aiming to reduce or inhibit the IFN-1 production and its effects may be a target for future treatment plans. Activated aryl hydrocarbon receptor may interact with latent Epstein-Barr virus (EBV) infection, which in turn may predispose to the development of Sjögren's syndrome. It is estimated that the population is 95% positive for EBV serology. Microbial factors may incite autoimmune disease. Although this hypothesis is proven in a few illnesses such as rheumatic fever, there is no definitive evidence of an infectious environmental trigger in Sjögren's syndrome. However, there are circumstantial data with regard to viruses and several potential mechanisms of disease. These include antigen mimicry, polyclonal lymphocyte activation, and infection-mediated innate end-organ inflammation. In addition, hepatitis C virus infection clearly causes a Sjögren's-syndrome-like illness.Data continue to implicate viral infection in the cause of Sjögren's syndrome, but there are no definitive studies incriminating a particular virus." @default.
- W2017454918 created "2016-06-24" @default.
- W2017454918 creator A5023217115 @default.
- W2017454918 creator A5032524206 @default.
- W2017454918 date "2013-07-01" @default.
- W2017454918 modified "2023-10-14" @default.
- W2017454918 title "Autoimmunity and infection in Sjögren's syndrome" @default.
- W2017454918 cites W112689046 @default.
- W2017454918 cites W1528070988 @default.
- W2017454918 cites W1552769771 @default.
- W2017454918 cites W1766423076 @default.
- W2017454918 cites W1950901136 @default.
- W2017454918 cites W1964176015 @default.
- W2017454918 cites W1966736991 @default.
- W2017454918 cites W1968338988 @default.
- W2017454918 cites W1975184667 @default.
- W2017454918 cites W1975288439 @default.
- W2017454918 cites W1978556684 @default.
- W2017454918 cites W1979858212 @default.
- W2017454918 cites W1980663809 @default.
- W2017454918 cites W1982667989 @default.
- W2017454918 cites W1987576902 @default.
- W2017454918 cites W1993003564 @default.
- W2017454918 cites W1996034968 @default.
- W2017454918 cites W2002289451 @default.
- W2017454918 cites W2004300336 @default.
- W2017454918 cites W2004522121 @default.
- W2017454918 cites W2006772331 @default.
- W2017454918 cites W2007973442 @default.
- W2017454918 cites W2008383971 @default.
- W2017454918 cites W2008508478 @default.
- W2017454918 cites W2010615107 @default.
- W2017454918 cites W2015545119 @default.
- W2017454918 cites W2016447788 @default.
- W2017454918 cites W2018577190 @default.
- W2017454918 cites W2019842770 @default.
- W2017454918 cites W2023227165 @default.
- W2017454918 cites W2025024675 @default.
- W2017454918 cites W2025591938 @default.
- W2017454918 cites W2028092896 @default.
- W2017454918 cites W2030739472 @default.
- W2017454918 cites W2036139759 @default.
- W2017454918 cites W2036585364 @default.
- W2017454918 cites W2039301421 @default.
- W2017454918 cites W2040967551 @default.
- W2017454918 cites W2043318620 @default.
- W2017454918 cites W2047558287 @default.
- W2017454918 cites W2049933473 @default.
- W2017454918 cites W2052467883 @default.
- W2017454918 cites W2057940890 @default.
- W2017454918 cites W2064460845 @default.
- W2017454918 cites W2064967094 @default.
- W2017454918 cites W2067052679 @default.
- W2017454918 cites W2076118745 @default.
- W2017454918 cites W2079210000 @default.
- W2017454918 cites W2083246359 @default.
- W2017454918 cites W2084800620 @default.
- W2017454918 cites W2089647984 @default.
- W2017454918 cites W2092948080 @default.
- W2017454918 cites W2093102863 @default.
- W2017454918 cites W2098838373 @default.
- W2017454918 cites W2101315881 @default.
- W2017454918 cites W2101363646 @default.
- W2017454918 cites W2103273228 @default.
- W2017454918 cites W2107510741 @default.
- W2017454918 cites W2108941459 @default.
- W2017454918 cites W2108953680 @default.
- W2017454918 cites W2111631948 @default.
- W2017454918 cites W2113742350 @default.
- W2017454918 cites W2114776537 @default.
- W2017454918 cites W2122173657 @default.
- W2017454918 cites W2123877252 @default.
- W2017454918 cites W2126841260 @default.
- W2017454918 cites W2129961117 @default.
- W2017454918 cites W2133795774 @default.
- W2017454918 cites W2136394997 @default.
- W2017454918 cites W2139347834 @default.
- W2017454918 cites W2139996412 @default.
- W2017454918 cites W2148526322 @default.
- W2017454918 cites W2148670511 @default.
- W2017454918 cites W2152065787 @default.
- W2017454918 cites W2160183769 @default.
- W2017454918 cites W2160470907 @default.
- W2017454918 cites W2167906696 @default.
- W2017454918 cites W2169190640 @default.
- W2017454918 cites W2169378514 @default.
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- W2017454918 doi "https://doi.org/10.1097/bor.0b013e32836200d2" @default.
- W2017454918 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4410971" @default.
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