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- W2017458950 abstract "The antioxidants butylated hydroxytoluene (BHT) and ethoxyquin protected rats against intoxication and mortality normally produced by hexachlorophene (HCP, 100 mg/kg). BHT also prevented the elevation of cerebrospinal fluid pressure, a central nervous system effect of HCP poisoning. In addition, both phenobarbital and SKF-525A protected against HCP poisoning, with the barbiturate also offering significant protection against triethyltin. L-Ascorbic acid, vitamin E, N,N-diphenyl-p-phenylenediamine and reduced and oxidized glutathione over a range of doses were ineffective in preventing HCP lethality. The protective effect of phenobarbital against HCP and triethyltin intoxication further supports existing evidence of a common or similar mechanism of toxic action for these two structurally dissimilar compounds." @default.
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- W2017458950 date "1984-03-01" @default.
- W2017458950 modified "2023-09-27" @default.
- W2017458950 title "Protection with butylated hydroxytoluene and other compounds against intoxication and mortality caused by hexachlorophene" @default.
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- W2017458950 doi "https://doi.org/10.1016/0278-6915(84)90125-x" @default.
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