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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017477675> ?p ?o ?g. }

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• W2017477675 abstract "Conformational changes of channel activation: Five enhanced green fluorescent protein (EGFP) molecules (green cylinders) were integrated into the intracellular part of the homopentameric ionotropic 5-HT3 receptor. This allowed the detection of extracellular binding of fluorescent ligands (•) to EGFP by FRET, and also enabled the quantification of agonist-induced conformational changes in the intracellular region of the receptor by homo-FRET between EGFPs. The approach opens novel ways for probing receptor activation and functional screening of therapeutic compounds." @default.
• W2017477675 created "2016-06-24" @default.
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• W2017477675 date "2005-11-30" @default.
• W2017477675 modified "2023-10-16" @default.
• W2017477675 title "Ligand Binding Transmits Conformational Changes across the Membrane‐Spanning Region to the Intracellular Side of the 5‐HT₃ Serotonin Receptor" @default.
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• W2017477675 doi "https://doi.org/10.1002/cbic.200500191" @default.
• W2017477675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16254942" @default.
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