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- W2017488536 abstract "Drug disposition is highly regulated by membrane transporters. Some transporter-mediated drug–drug interactions (DDIs) may not manifest themselves in changes in systemic exposure but rather in changes in tissue exposure of drugs. To better assess the impact of transporter-mediated DDIs in tissues, positron emission tomography (PET)—a noninvasive imaging method—plays an increasingly important role. In this article, we provide examples of how PET can be used to assess transporter-mediated DDIs in different organs. Clinical Pharmacology & Therapeutics (2014); 96 2, 206–213. doi:10.1038/clpt.2014.70" @default.
- W2017488536 created "2016-06-24" @default.
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- W2017488536 date "2014-03-28" @default.
- W2017488536 modified "2023-09-23" @default.
- W2017488536 title "Using Positron Emission Tomography to Study Transporter-Mediated Drug–Drug Interactions in Tissues" @default.
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- W2017488536 doi "https://doi.org/10.1038/clpt.2014.70" @default.
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