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• W2017508629 endingPage "11" @default.
• W2017508629 startingPage "6" @default.
• W2017508629 abstract "Chromatin dynamics play a major role in regulating genetic processes. Now, accumulating data suggest that chromatin structure may also affect the mechanical properties of the nucleus and cell migration. Global chromatin organization appears to modulate the shape, the size and the stiffness of the nucleus. Directed-cell migration, which often requires nuclear reshaping to allow passage of cells through narrow openings, is dependent not only on changes in cytoskeletal elements but also on global chromatin condensation. Conceivably, during cell migration a physical link between the chromatin and the cytoskeleton facilitates coordinated structural changes in these two components. Thus, in addition to regulating genetic processes, we suggest that alterations in chromatin structure could facilitate cellular reorganizations necessary for efficient migration." @default.
• W2017508629 created "2016-06-24" @default.
• W2017508629 creator A5025814998 @default.
• W2017508629 creator A5039096120 @default.
• W2017508629 date "2011-01-01" @default.
• W2017508629 modified "2023-10-18" @default.
• W2017508629 title "The role of chromatin structure in cell migration" @default.
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• W2017508629 doi "https://doi.org/10.1016/j.tcb.2010.09.002" @default.
• W2017508629 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3014417" @default.
• W2017508629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20951589" @default.
• W2017508629 hasPublicationYear "2011" @default.
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