Matches in SemOpenAlex for { <https://semopenalex.org/work/W2017510271> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2017510271 endingPage "908" @default.
- W2017510271 startingPage "899" @default.
- W2017510271 abstract "Somatic and meiotic chromosomes have been studied prospectively in 200 subfertile males. The results have been correlated with clinical, seminal and endocrinological features, with histological findings in testicular biopsies and with response to conventional treatment. Somatic chromosome abnormalities were found in 3·5% of cases and variants of the Y chromosome were found in 10·5 %. Definite abnormalities in meiotic chromosomes were observed in 20% of these patients, including supernumerary chromosomes, low chiasma frequency and asynapsis, and translocations. Many of these abnormalities occurred as mosaics, presumably a result of meiotic mutation. In 4 cases, a previously unrecognised abnormality in pachynemas has been defined. Absence of meiosis was found in 12% of cases, which correlated well with the histological findings of germinal cell aplasia and elevated urinary FSH levels. It is concluded from this preliminary analysis that abnormalities in meiosis may account for the decreased spermatogenesis and poor response to treatment in at least 20% of subfertile men. However, these abnormalities do not constitute a contra-indication to treatment as normal pregnancies can still be produced, in a few cases albeit, sometimes requiring monitoring." @default.
- W2017510271 created "2016-06-24" @default.
- W2017510271 creator A5046822874 @default.
- W2017510271 creator A5047156950 @default.
- W2017510271 creator A5072218997 @default.
- W2017510271 creator A5076371663 @default.
- W2017510271 creator A5078027654 @default.
- W2017510271 date "1975-12-01" @default.
- W2017510271 modified "2023-10-17" @default.
- W2017510271 title "200 Infertile Males: Correlation of Chromosome, Histological, Endocrine and Clinical Studies" @default.
- W2017510271 cites W1982103555 @default.
- W2017510271 cites W2005486495 @default.
- W2017510271 cites W2028375026 @default.
- W2017510271 cites W2081186236 @default.
- W2017510271 cites W2082385633 @default.
- W2017510271 cites W2089474646 @default.
- W2017510271 doi "https://doi.org/10.1111/j.1464-410x.1975.tb04074.x" @default.
- W2017510271 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1222357" @default.
- W2017510271 hasPublicationYear "1975" @default.
- W2017510271 type Work @default.
- W2017510271 sameAs 2017510271 @default.
- W2017510271 citedByCount "39" @default.
- W2017510271 countsByYear W20175102712016 @default.
- W2017510271 countsByYear W20175102712017 @default.
- W2017510271 crossrefType "journal-article" @default.
- W2017510271 hasAuthorship W2017510271A5046822874 @default.
- W2017510271 hasAuthorship W2017510271A5047156950 @default.
- W2017510271 hasAuthorship W2017510271A5072218997 @default.
- W2017510271 hasAuthorship W2017510271A5076371663 @default.
- W2017510271 hasAuthorship W2017510271A5078027654 @default.
- W2017510271 hasConcept C104317684 @default.
- W2017510271 hasConcept C118552586 @default.
- W2017510271 hasConcept C123765429 @default.
- W2017510271 hasConcept C125832826 @default.
- W2017510271 hasConcept C134018914 @default.
- W2017510271 hasConcept C134305767 @default.
- W2017510271 hasConcept C138626823 @default.
- W2017510271 hasConcept C148196450 @default.
- W2017510271 hasConcept C16685009 @default.
- W2017510271 hasConcept C2777688143 @default.
- W2017510271 hasConcept C2779234561 @default.
- W2017510271 hasConcept C30481170 @default.
- W2017510271 hasConcept C50965678 @default.
- W2017510271 hasConcept C54355233 @default.
- W2017510271 hasConcept C71924100 @default.
- W2017510271 hasConcept C86803240 @default.
- W2017510271 hasConceptScore W2017510271C104317684 @default.
- W2017510271 hasConceptScore W2017510271C118552586 @default.
- W2017510271 hasConceptScore W2017510271C123765429 @default.
- W2017510271 hasConceptScore W2017510271C125832826 @default.
- W2017510271 hasConceptScore W2017510271C134018914 @default.
- W2017510271 hasConceptScore W2017510271C134305767 @default.
- W2017510271 hasConceptScore W2017510271C138626823 @default.
- W2017510271 hasConceptScore W2017510271C148196450 @default.
- W2017510271 hasConceptScore W2017510271C16685009 @default.
- W2017510271 hasConceptScore W2017510271C2777688143 @default.
- W2017510271 hasConceptScore W2017510271C2779234561 @default.
- W2017510271 hasConceptScore W2017510271C30481170 @default.
- W2017510271 hasConceptScore W2017510271C50965678 @default.
- W2017510271 hasConceptScore W2017510271C54355233 @default.
- W2017510271 hasConceptScore W2017510271C71924100 @default.
- W2017510271 hasConceptScore W2017510271C86803240 @default.
- W2017510271 hasIssue "7" @default.
- W2017510271 hasLocation W20175102711 @default.
- W2017510271 hasLocation W20175102712 @default.
- W2017510271 hasOpenAccess W2017510271 @default.
- W2017510271 hasPrimaryLocation W20175102711 @default.
- W2017510271 hasRelatedWork W1980284669 @default.
- W2017510271 hasRelatedWork W2014896482 @default.
- W2017510271 hasRelatedWork W2080206206 @default.
- W2017510271 hasRelatedWork W2144125806 @default.
- W2017510271 hasRelatedWork W2145303545 @default.
- W2017510271 hasRelatedWork W2158243566 @default.
- W2017510271 hasRelatedWork W2326141489 @default.
- W2017510271 hasRelatedWork W2612577867 @default.
- W2017510271 hasRelatedWork W2887795067 @default.
- W2017510271 hasRelatedWork W4250235766 @default.
- W2017510271 hasVolume "47" @default.
- W2017510271 isParatext "false" @default.
- W2017510271 isRetracted "false" @default.
- W2017510271 magId "2017510271" @default.
- W2017510271 workType "article" @default.